The Effects of Naturalistic Light on Post Stroke Complications Related Brain Areas in Stroke Patients During Admission for Rehabilitation.
NCT06922409, Not applicable, Recruiting, Copenhagen University Hospital, Rigshospitalet
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | The Effects of Naturalistic Light on Post Stroke Complications Related Brain Areas in Stroke Patients During Admission for Rehabilitation. | ClinicalTrials.gov |
| NCT number | NCT06922409 | ClinicalTrials.gov |
| Status | Recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 45 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Copenhagen University Hospital, Rigshospitalet | ClinicalTrials.gov |
| Conditions | Post Stroke Depression, Post Stroke Fatigue, Circadian Dysregulation, Stroke | ClinicalTrials.gov |
| Interventions | Naturalistic Light Intervention | ClinicalTrials.gov |
| First posted | 2025-04-10 | ClinicalTrials.gov |
| Last updated | 2025-04-15 | ClinicalTrials.gov |
Registered outcomes 5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Fatigue and depression | From admission at the rehabilitation unit to the time of discharge aprox. 10 days. | Primary hypothesis: Naturalistic light reduce the major depression inventory questionnaire score and multidimensional fatigue inventory questionnaire score from baseline til discharge. Mood-related network will too show positive changes measured by whole brain resting-state connectivity in post-stroke patients compared with a control group without fatigue and depression. | ClinicalTrials.gov |
| Secondary | Cognitive function | From admission to the neurorehabilitation unit to the time of discharge aprox 10 days.. | Secondary hypothesis: Naturalistic light improves executive cognitive function and processing speed in test included in the Neuropsychology assessments (Verbal fluency, 1 minute each per test: Category fluency (animals) and lexical fluency (s words and a words), System Digit Modalities Test (SDMT), and Stroop test) and furthermore modifies cognitive related network activation measured by fMRI in post-stroke patients compared with a control group without cognitive impairment. | ClinicalTrials.gov |
| Secondary | Sleep quality | From admission to the neurorehabilitation unit to the time of discharge aprox. 10 days.. | Secondary hypothesis: Naturalistic light improves sleep quality from baseline to discharge measured by polysomnography and Pittsburgh Sleep Quality Index questionnaire in post-stroke patients compared with a control group without poor sleep quality. | ClinicalTrials.gov |
| Secondary | Hypocretin | From admission to the neurorehabilitation unit to the time of discharge aprox. 10 days.. | Secondary hypothesis: Naturalistic light increase hypocretin levels from baseline to discharge in post stroke patients with measured fatigue and sleepiness compared to a control group without fatigue and sleepiness. | ClinicalTrials.gov |
| Secondary | CFS inflammation | From admission to the neurorehabilitation unit to the time of discharge aprox. 10 days. | Secondary hypothesis: The severity of post stroke fatigue and post stroke depression is associated to the level of markers related to cerebral inflammation based on measured CFS inflammation and naturalistic light will decrease this inflammation compared to a control group without fatigue and depression. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 28430522 | BACKGROUND | PubMed |
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 3
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Category Fluency | Secondary outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Verbal Fluency | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)