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Trial · NCT06923826

Sacituzumab Govitecan in Metastatic Salivary Gland and Thyroid Cancers (SG-SGTC)

NCT06923826, Phase 2, Recruiting, National University Hospital, Singapore

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Sacituzumab Govitecan in Metastatic Salivary Gland and Thyroid Cancers (SG-SGTC). Trials, record NCT06923826. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06923826

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Sacituzumab Govitecan in Metastatic Salivary Gland and Thyroid Cancers (SG-SGTC)
NCT number
NCT06923826
Status
Recruiting
Phases
Phase 2
Enrollment
32 participants, estimated
Lead sponsor
National University Hospital, Singapore
Conditions
Salivary Gland Cancer, Thyroid Cancer
Interventions
Sacituzumab govitecan
First posted
2025-04-11
Last updated
2025-07-25

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryObjective response rate (ORR)Up to 3 yearsORR is defined as the as the percentage of participants with a complete response (CR) or partial response (PR) according to response evaluation criteria in solid tumours (RECIST) version 1.1.
SecondaryProgression free survival (PFS)From date of treatment assignment until first documented progression or date of death, whichever occurs earlier, assessed up to 3 yearsPFS is defined as the time from treatment assignment to disease progression or death, whichever occurs first
SecondaryIncidence of Treatment-Related Adverse Events (TRAEs)From date of informed consent till 90 days following the date of last dose of study treatment.The frequency and outcome of TRAEs as assessed and graded according to the CTCAE version 5.0.
Secondary6-months Disease control rate (DCR)Up to 6 months after initiating study treatment.
6-months DCR is defined to be the percentage of participants with a complete response (CR), partial response (PR) or stable disease (SD) noted as the objective response status, according to RECIST version 1.1, at 6 months after initiating study treatment.
SecondaryCorrelation of ORR with Trop-2 expression in tumour samplesUp to 3 yearsRelationship between ORR and Trop-2 expression levels measured in tumour samples.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers8

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
8879381BACKGROUNDPubMed
20858281BACKGROUNDPubMed
22006781BACKGROUNDPubMed
24795243BACKGROUNDPubMed
28709407BACKGROUNDPubMed
29543059BACKGROUNDPubMed
37633306BACKGROUNDPubMed
38843511BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06923826

GET https://conductscience.org/api/trials/v1/NCT06923826/registered