Trial · NCT06937866
Maintenance Zanzalintinib With Etoposide After HDCT in GCT
NCT06937866, Phase 1, Phase 2, Recruiting, Indiana University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Maintenance Zanzalintinib With Etoposide After HDCT in GCT. Trials, record NCT06937866. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06937866
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Maintenance Zanzalintinib With Etoposide After HDCT in GCT
- NCT number
- NCT06937866
- Status
- Recruiting
- Phases
- Phase 1, Phase 2
- Enrollment
- 38 participants, estimated
- Lead sponsor
- Indiana University
- Conditions
- Germ Cell Tumor
- Interventions
- Zanzalintinib, Etoposide Capsule
- First posted
- 2025-04-22
- Last updated
- 2025-11-21
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Phase 1: Rate of hematologic toxicity | 28 days | Rate of hematologic toxicity including neutropenia, anemia, or thrombocytopenia requiring intervention (transfusions or antibiotics) |
| Primary | Phase 1: Rate of non-hematologic toxicity | 28 days | Rate of non-hematologic toxicity |
| Primary | Phase II: 12-month Progression Free Survival | 12 months | 12-month PFS based on investigator determination of tumor progression (clinical, radiographic, and/or tumor markers including AFP and hCG) |
| Secondary | Phase II: 12-month Overall Survival (OS) | 12 months post time of registration | 12-month OS as determined from time of registration to death from any cause |
| Secondary | Phase II: Incidence of Adverse Events | Start of treatment until end of treatment safety assessments (up to 2 years) | Toxicity measured by the NCI Common Terminology Criteria for Adverse Events (CTCAE) v5.0 and need for treatment delay, dose reduction, or early discontinuation. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06937866
GET https://conductscience.org/api/trials/v1/NCT06937866/registered