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Trial · NCT06959511

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

NCT06959511, Phase 2, Recruiting, M.D. Anderson Cancer Center

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery. Trials, record NCT06959511. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06959511

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery
NCT number
NCT06959511
Status
Recruiting
Phases
Phase 2
Enrollment
45 participants, estimated
Lead sponsor
M.D. Anderson Cancer Center
Conditions
Neoadjuvant Treatment, Thyroid Cancer
Interventions
Zanzalintinib
First posted
2025-05-06
Last updated
2026-11-05

Source ClinicalTrials.gov

Registered outcomes1

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimarySafety and adverse eventsFrom baseline until completion of neoadjuvant therapy; an average of 6 months
Defined as the proportion of patients who have a MR, PR, or CR per modified RECIST 1.1. CR and PR are defined using the same criteria as in RECIST 1.1. MR is defined as a 15% or greater decrease in the sum of the longest diameters of target lesions but not a PR. The MR+PR+CR response rate will be determined by dividing the number of patients with modified RECIST-based MR, PR, or CR divided by the number of evaluable patients

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06959511

GET https://conductscience.org/api/trials/v1/NCT06959511/registered