Trial · NCT06968559
Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns
NCT06968559, Phase 3, Recruiting, Nantes University Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns. Trials, record NCT06968559. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06968559
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns
- NCT number
- NCT06968559
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 478 participants, estimated
- Lead sponsor
- Nantes University Hospital
- Conditions
- Severe Burns
- Interventions
- Dexamethasone, Placebo
- First posted
- 2025-05-13
- Last updated
- 2025-11-18
Source ClinicalTrials.gov
Registered outcomes20
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Major complications | 28 days | It's a hierarchic procedure. Major complications defined as moderate to severe ARDS (using Berlin definition criteria) or AKI KDIGO 2 to 3 within 28 days |
| Primary | All-cause mortality at day 90 | 90 days | |
| Secondary | Hospital-acquired infections | 28 days | Hospital-acquired pneumonia (using the joint definition from the Infectious Diseases Society of America and American Thoracic Society) within 28 days |
| Secondary | Hospital-acquired infections | 28 days | Catheter-related bloodstream infections within 28 daysDiseases Society of America and American Thoracic Society) within 28 days |
| Secondary | Hospital-acquired infections | 28 days | other infections, including skin infections (diagnosis confirmed by an independent adjudication committee) with or without bacteraemia within 28 days |
| Secondary | Hospital-acquired infections | 28 days | Antibiotic-free days on day 28 |
| Secondary | Respiratory complications | 28 days | ARDS (using Berlin Criteria definition) on day 28 |
| Secondary | Respiratory complications | 28 days | Invasive ventilator-free days on day 28 |
| Secondary | ICU Length-of-Stay | 28 days | ICU Length-of-Stay |
| Secondary | Hospital Length-of-Stay | 28 days | Hospital Length-of-Stay |
1 to 10 of 20Source ClinicalTrials.gov
See all 20 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 42337788 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06968559
GET https://conductscience.org/api/trials/v1/NCT06968559/registered