Trial · NCT06969573
Inhaled Treprostinil for Dyspnea and Exercise Intolerance in Mild COPD
NCT06969573, Phase 2, Active not recruiting, University of Alberta
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Inhaled Treprostinil for Dyspnea and Exercise Intolerance in Mild COPD. Trials, record NCT06969573. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06969573
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Inhaled Treprostinil for Dyspnea and Exercise Intolerance in Mild COPD
- NCT number
- NCT06969573
- Status
- Active not recruiting
- Phases
- Phase 2
- Enrollment
- 20 participants, actual
- Lead sponsor
- University of Alberta
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease)
- Interventions
- Placebo, Treprostinil Inhalation Solution 36 mcg, Treprostinil Inhalation Solution 78 mcg
- First posted
- 2025-05-14
- Last updated
- 2026-11-05
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Exercise tolerance | Within 30-45 minutes post dose | Time to symptom limitation/exhaustion during a constant work rate test. |
| Primary | Exertional dyspnea | Within 30-45 minutes post dose | Maximal perceived breathing discomfort during exercise |
| Primary | Ventilatory efficiency | Within 30-45 minutes post dose | Nadir value of the ratio between ventilation and the rate of CO2 production (Ve/VCO2 nadir) |
| Secondary | Lung diffusing capacity | Within 15-30 minutes post dose | Lung diffusing capacity (DLCO) will be measured using six-second, advanced DLCO techniques. |
| Secondary | Pulmonary capillary blood volume (Vc) | Within 15-30 minutes post dose | Pulmonary capillary blood volume (Vc) will be measured using six-second, advanced DLCO techniques. |
| Secondary | Diffusing membrane Capacity (Dm) | Within 15-30 minutes post dose | Diffusing membrane capacity will be measured using six-second, advanced DLCO techniques. |
| Secondary | Cardiac structure and function | Within 15-30 minutes post dose | echocardiography-derived right ventricular systolic pressure |
| Secondary | Pulmonary vascular volumes | Day 6 | Chest computed tomography (CT) scan |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06969573
GET https://conductscience.org/api/trials/v1/NCT06969573/registered