Trial · NCT06974916
EMBRACE Tremor BiFUS
NCT06974916, Not applicable, Recruiting, InSightec
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. EMBRACE Tremor BiFUS. Trials, record NCT06974916. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06974916
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- EMBRACE Tremor BiFUS
- NCT number
- NCT06974916
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 100 participants, estimated
- Lead sponsor
- InSightec
- Conditions
- Essential Tremor
- Interventions
- Staged bilateral Exablate thalamotomy, Local standard medical treatment after previous Exablate unilateral thalamotomy.
- First posted
- 2025-05-16
- Last updated
- 2026-08-31
Source ClinicalTrials.gov
Registered outcomes17
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Treated Upper Limb Clinical Rating Scale for Tremor (CRST) (A+B) (0-28) score for the treated side. | 6 Months | The primary endpoint is the difference of the Treated Upper Limb CRST (A+B) score between groups at 6 months. Higher score means a worse tremor. |
| Secondary | Treated Upper Limb Clinical Rating Scale for Tremor (CRST) (A+B) (0-28) score as assessed by the blinded reviewers of the video-recordings. | 6 Months, 12 Months | Between group comparison through month 6 and within group comparison vs baseline up to month 12 in Treated Upper Limb CRST (A+B) score as assessed by the blinded reviewers of the video-recordings. Higher score means a worse tremor. |
| Secondary | Clinical Rating Scale for Tremor (CRST) part A (0-76) | 6 Months, 12 Months | Between group comparison through month 6 and within group comparison vs baseline up to month 12 in resting, postural, and action tremors of all items as measured by CRST part A. Higher score means a worse tremor. |
| Secondary | Bilateral Upper Limb Clinical Rating Scale for Tremor (CRST) (A+B) (0-56) | 6 Months, 12 Months | Between group comparison through month 6 and within group comparison vs baseline up to month 12 in Bilateral Upper Limb CRST (A+B). Higher score means a worse tremor. |
| Secondary | Total Clinical Rating Scale for Tremor (CRST) (A+B) (0-116) | 6 Months, 12 Months | Between group comparison through month 6 and within group comparison vs baseline up to month 12 in Total CRST (A+B). Higher score means a worse tremor. |
| Secondary | Clinical Rating Scale for Tremor (CRST) part C (0-32) | 6 Months, 12 Months | Between group comparison through month 6 and within group comparison vs baseline up to month 12 in functional disabilities as measured by CRST part C. Higher score means a worse tremor. |
| Secondary | Axial Clinical Rating Scale for Tremor (CRST) (0-20) | 6 Months, 12 Months | Between group comparison through month 6 and within group comparison vs baseline up to month 12 in Axial CRST defined as face, tongue, head tremor and voice items of CRST part A |
| Secondary | Quality of life questionnaire | 6 Months, 12 Months | Between group comparison through month 6 and within group comparison vs baseline up to month 12 in disease specific QOL |
| Secondary | Change of tremor medication | 6 Months, 12 Months | Between group comparison through month 6 and within group comparison vs baseline up to month 12 in tremor medication change |
| Secondary | Safety: Incidence and frequency of adverse events related to the treatment. | 6 Months, 12 Months | Incidence and frequency of adverse events related to the treatment and/or procedure. The investigator will capture any untoward events in the case report forms along with severity, duration, and resolution, and whether the event is considered serious. The severity of adverse events will be categorized according to the definition of adverse events from the International Organization for Standardization (ISO). |
1 to 10 of 17Source ClinicalTrials.gov
See all 17 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06974916
GET https://conductscience.org/api/trials/v1/NCT06974916/registered