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Trial · NCT06982859

Registered outcomes13

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange from Baseline in Total Clamp Disposition Index (cDI) for Comparison of Retatrutide With PlaceboBaseline, Week 28Change from baseline in total cDI for comparison of retatrutide with placebo
SecondaryChange from Baseline in cDI for Comparison Between Retatrutide and SemaglutideBaseline, Week 28Change from baseline in total cDI for comparison between retatrutide and semaglutide
SecondaryChange from Baseline in Hyperinsulinemic Euglycemic Clamp M-valueBaseline, Week 28Change from baseline in hyperinsulinemic euglycemic clamp M-value
SecondaryChange from Baseline in First Phase Incremental Insulin Secretion Rate (ISR)Baseline, Week 28Change from baseline in first phase ISR.
SecondaryChange from Baseline in Second Phase Total ISRBaseline, Week 28Change from baseline in second phase total ISR
SecondaryChange from Baseline in Total ISRBaseline, Week 28Change from baseline in total ISR
SecondaryChange from Baseline in Insulin Response to Arginine [Incremental Insulin Area Under the Curve (AUC) arginine, 0-10minutes]Baseline, Week 28Change from baseline in insulin response to arginine \[Incremental Insulin AUC arginine, 0-10minutes\].
SecondaryChange from Baseline in Insulin Response to Arginine (Incremental Insulin AUC arginine, 0-30minutes)Baseline, Week 28Change from baseline in insulin response to arginine (Incremental Insulin AUC arginine, 0-30minutes).
SecondaryChange from Baseline in Beta-cell (β-cell) Glucose Sensitivity (GS)Baseline, Week 28Change from baseline in β-cell GS.
SecondaryChange from Baseline in β-cell Glucose Sensitivity (GS) from Standardized Mixed-Meal Tolerance Test (sMMTT)Baseline, Week 28Change from baseline in β-cell GS from sMMTT.
SecondaryChange from Baseline in ISR at Fixed Glucose Concentration (ISRg) from sMMTTBaseline, Week 28Change from baseline in ISR at fixed glucose concentration (ISRg) from sMMTT
SecondaryChange from Baseline Fasting Glucose During sMMTT (Total and Incremental AUC0-240min)Baseline, Week 28Change from baseline fasting glucose during sMMTT (total and incremental AUC0-240min)
SecondaryChange from Baseline Postmeal Glucose During sMMTT (Total and Incremental AUC0-240min)Baseline, Week 28Change from baseline postmeal glucose during sMMTT (total and incremental AUC0-240min)

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT06982859/registered