Trial · NCT06997952
Febuxostat Effect on Chronic Kidney Disease Progression And Carotid Intima-Media Thickness
NCT06997952, Phase 1, Completed, Ain Shams University
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Febuxostat Effect on Chronic Kidney Disease Progression And Carotid Intima-Media Thickness. Trials, record NCT06997952. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06997952
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Febuxostat Effect on Chronic Kidney Disease Progression And Carotid Intima-Media Thickness
- NCT number
- NCT06997952
- Status
- Completed
- Phases
- Phase 1
- Enrollment
- 50 participants, actual
- Lead sponsor
- Ain Shams University
- Conditions
- Carotid Intima- Media Thickness
- Interventions
- Febuxostat 40 mg
- First posted
- 2025-05-31
- Last updated
- 2026-07-29
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in estimated glomerular filtration rate (eGFR) from baseline to 12 weeks | 3 months | Change in estimated glomerular filtration rate (eGFR), calculated using the CKD-EPI equation and expressed as mL/min/1.73 m², from baseline to 12 weeks following administration of febuxostat compared with the control group. |
| Primary | Change in proteinuria from baseline to 12 weeks | 3 months | Change in proteinuria, assessed by the urine protein-to-creatinine ratio (Pr/Cr ratio, mg/g), from baseline to 12 weeks following administration of febuxostat compared with the control group. |
| Secondary | Change in carotid intima-media thickness (CIMT) measured by carotid duplex from baseline to 12 weeks | 3 months | Change in carotid intima-media thickness (CIMT), assessed by carotid duplex imaging, from baseline to 12 weeks following administration of febuxostat compared with the control group. CIMT will be measured in millimetres (mm) using a standardized carotid duplex protocol. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06997952
GET https://conductscience.org/api/trials/v1/NCT06997952/registered