Trial · NCT07031518
Pilot Study to Identify and Validate Digital Biomarkers in Osteoarthritis of the Knee
NCT07031518, Not applicable, Completed, Centre Hospitalier Universitaire de Liege
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Pilot Study to Identify and Validate Digital Biomarkers in Osteoarthritis of the Knee. Trials, record NCT07031518. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07031518
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Pilot Study to Identify and Validate Digital Biomarkers in Osteoarthritis of the Knee
- NCT number
- NCT07031518
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 43 participants, actual
- Lead sponsor
- Centre Hospitalier Universitaire de Liege
- Conditions
- Osteoarthritis of the Knee
- Interventions
Syde, The Self-Paced 40-meter Walk Test (SPWT), 30-second chair stand test (30s-CST), The Timed up and go test (TUG), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC 3.1), Patient global impression of severity (PGI-S), Pain Level Diary, Qualitative Interview
- First posted
- 2025-06-22
- Last updated
- 2026-03-24
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Total Recording Time Over 2 Months | 2 months | Total number of hours recorded by the Syde® wearable device over a 2-month period. |
| Primary | Median Daily Recording Time | 2 months | Median number of hours recorded per day by the Syde® device over the 2-month period. |
| Primary | Days to Reach 180 Recording Hours | 2 months | Number of days required to reach 180 hours of recording, considered the optimal threshold for analysis. |
| Primary | Intra-Class Correlation of Syde® Outcomes | Entire recording period over 2 months | Intra-Class Correlation (ICC) of each Syde® outcome calculated over slices of x hours (x = 10 to 90) of data per patient to assess reliability. |
| Secondary | Correlation Between Syde® Variables and WOMAC 3.1 Scores | Baseline and 2 months | Spearman correlation between digital variables and WOMAC 3.1 scores at 2 months. |
| Secondary | Correlation Between Syde® Variables and Timed Tests | Baseline and 2 months | Correlation between digital variables and results from 40 m self-paced test, 30 s chair stand test, and timed up and go test. |
| Secondary | Correlation Between Syde® Variables and Kellgren-Lawrence Grade | Baseline | Spearman correlation between digital variables and Kellgren-Lawrence grade. |
| Secondary | Discriminative Power of Syde® Variables | Entire recording period over 2 months | Differences in Syde® outcomes between patients and controls, and among subgroups based on WOMAC 3.1 scores. |
| Secondary | Qualitative Interview on Mobility and Usability | Baseline and Month 2 | Qualitative data from interviews exploring mobility limitations, important measures, and impact on daily life. |
| Secondary | Stiffness Index Based on Immobility | Entire recording period over 2 months | Ratio of outcome measures after 0.5-3 hours of immobility (≥10 minutes) compared to full-day values excluding immobility periods. |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07031518
GET https://conductscience.org/api/trials/v1/NCT07031518/registered