Trial · NCT07035301
Application of Low-dose Muscle Relaxants in Bronchoscopic Interventional Procedures
NCT07035301, Not applicable, Completed, Harbin Medical University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Application of Low-dose Muscle Relaxants in Bronchoscopic Interventional Procedures. Trials, record NCT07035301. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07035301
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Application of Low-dose Muscle Relaxants in Bronchoscopic Interventional Procedures
- NCT number
- NCT07035301
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 153 participants, actual
- Lead sponsor
- Harbin Medical University
- Conditions
- Disease of Respiratory System
- Interventions
- Normal Saline (Placebo), Lidocaine Intravenous Infusion, Remimazolam Tosilate, Remifentanil, Rocuronium (0.15mg/kg/body mass)
- First posted
- 2025-06-25
- Last updated
- 2026-10-19
Source ClinicalTrials.gov
Registered outcomes40
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The incidence rate of laryngeal spasm | From initiation of anesthesia induction to completion of bronchoscope insertion | Observe the degree of glottic opening (grade I: glottis opens well; grade II: glottis opens \>⅔, mild laryngospasm; grade III: glottis opens ⅓-⅔, moderate laryngospasm; grade IV: glottis opens ≤⅓ or is completely closed, severe laryngospasm).Grades III and IV were defined as laryngospasm. |
| Secondary | The severity of postoperative sore throat | When the patient regained consciousness (assessed up to 30 minutes after surgery) | The patient's sore throat was evaluated using the visual analogue scale. A 10-cm movable ruler with 10 marks was used, with the two ends marked at 0 and 10 respectively. The patient was asked to mark the corresponding position on the ruler that represented their degree of pain. 0 represented no pain, and 10 represented extremely painful. |
| Secondary | Dysphagia | When the patient regained consciousness (assessed up to 30 minutes after surgery) | After the surgery, inquire whether the patient has any difficulty in swallowing. |
| Secondary | The incidence of oxygen desaturation (SpO₂ < 92%) during mask ventilation | during anesthesia induction | The number of patients with SpO₂ \< 92% during mask ventilation in the induction period / total number of patients in the group |
| Secondary | Grading of body movement during bronchoscope insertion | At the beginning of the operation | Grade 1: Slight movement that does not interfere with the procedure. Grade 2: Pronounced movement that interferes with the procedure. Grade 3: Thrashing or vigorous movement that significantly interferes with the procedure. |
| Secondary | Grading of chest wall rigidity | During the process of anesthesia induction | Mild: No difficult ventilation but with stiffness of the limbs or abdominal wall. Moderate: Difficult ventilation accompanied by noticeable limb stiffness or abdominal wall rigidity. Severe: Inability to ventilate with significant limb stiffness or abdominal wall rigidity. |
| Secondary | Difficult facemask ventilation | During the process of anesthesia induction | Grade A represented the presence of an end-tidal carbon dioxide (PETCO₂) waveform plateau; Grade B, the absence of a plateau but with a PETCO₂ value ≥ 10 mmHg; Grade C, the absence of a plateau and a PETCO₂ value \< 10 mmHg; and Grade D, the absence of a detectable PETCO₂ waveform. Grades C and D were classified as difficult facemask ventilation. |
| Secondary | The incidence rate of choking cough when the bronchoscope first enters the trachea | At the beginning of the operation | Grade 0: no choking cough response; grade 1: single mild choking cough response; grade 2: multiple mild choking cough responses(\<=5s); grade 3: severe choking cough response(\>5s). |
| Secondary | Nausea | When the patient regained consciousness (assessed up to 30 minutes after surgery) | After the surgery, ask the patient if they are experiencing nausea. |
| Secondary | Number of laryngeal mask placements | During the process of anesthesia induction | Record the number of times the laryngeal mask is inserted when it is placed. |
1 to 10 of 40Source ClinicalTrials.gov
See all 40 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07035301
GET https://conductscience.org/api/trials/v1/NCT07035301/registered?page=2