Trial · NCT07043270
24BRO681 : Alternating Gnp and mFOLFIRINOX for BR-PDAC
NCT07043270, Phase 2, Recruiting, Dartmouth-Hitchcock Medical Center
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. 24BRO681 : Alternating Gnp and mFOLFIRINOX for BR-PDAC. Trials, record NCT07043270. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07043270
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- 24BRO681 : Alternating Gnp and mFOLFIRINOX for BR-PDAC
- NCT number
- NCT07043270
- Status
- Recruiting
- Phases
- Phase 2
- Enrollment
- 35 participants, estimated
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Conditions
- Pancreas Adenocarcinoma
- Interventions
- Nab-paclitaxel + Gemcitabine, modified FOLFIRINOX (mFOLFIRINOX)
- First posted
- 2025-06-29
- Last updated
- 2026-08-06
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | One-year event-free survival (1y-EFS) | I year | One-year EFS is defined as completing one year from enrollment without the occurrence of any of the following events: 1) disease progression per Response Evaluation Criteria in Solid Tumors (RECIST), 2) surgery with R2 resection, 3) recurrent disease following surgery, or 4) death from any cause. |
| Secondary | Proportion of patients who complete the study intervention | 1 year | |
| Secondary | Proportion of patients who require dose modification | 1 year | |
| Secondary | Proportion of patients who undergo surgery | 1 year | |
| Secondary | Radiographic response (unconfirmed) after chemotherapy, per RECIST | 1 year | |
| Secondary | Surgical resection rate (R0, R1 and R2 resection) | 1 year | |
| Secondary | Pathologic response observed in the surgical specimen | 1 year | |
| Secondary | Recurrence-free survival (RFS) in patients who undergo surgery | 1 year | |
| Secondary | EFS (Event Free Survival) and OS (Overall Survival) | 1 year | |
| Secondary | Trend of CA19-9 | 1 year |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07043270
GET https://conductscience.org/api/trials/v1/NCT07043270/registered