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Trial · NCT07072208

Pomalidomide, Rituximab and Orelabrutinib Combined With Polatuzumab Vedotin in the Treatment of Newly Diagnosed Elderly Patients With DLBCL

NCT07072208, Not applicable, Recruiting, The First Affiliated Hospital of Soochow University

3 sourcestrials-2026-11-12-0.4.0

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ConductScience Library. Pomalidomide, Rituximab and Orelabrutinib Combined With Polatuzumab Vedotin in the Treatment of Newly Diagnosed Elderly Patients With DLBCL. Trials, record NCT07072208. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07072208

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Pomalidomide, Rituximab and Orelabrutinib Combined With Polatuzumab Vedotin in the Treatment of Newly Diagnosed Elderly Patients With DLBCL
NCT number
NCT07072208
Status
Recruiting
Phases
Not applicable
Enrollment
43 participants, estimated
Lead sponsor
The First Affiliated Hospital of Soochow University
Conditions
Diffuse Large B-Cell Lymphoma
Interventions
Induction therapy-Pro regimen, Consolidation therapy-Pro-pola regimen
First posted
2025-07-18
Last updated
2025-07-18

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryComplete response rate(CRR)At the end of 6 cycles of Pro-pola regimen (each cycle is 21 days)The rate of patients who achieved CR after 6 cycles of Pro-pola regimen
SecondaryObjective response rate(ORR)At the end of 6 cycles of Pro-pola regimen (each cycle is 21 days)The rate of patients who achieved CR or PR after 6 cycles of Pro-pola regimen
Secondary2-year progression-free survival(PFS)From the enrollment to 2-year after the treatment of last patientPFS will be assessed from the start of the treament to date of progression, relapse, death or end of follow-up.
Secondary2-year overall survival(OS)From the enrollment to 2-year after the treatment of last patientOS will be assessed from the start the treatment to date of death or end of follow-up.
SecondaryMain adverse reactionsFrom the enrollment to 1 months after 6 cycles of Pro-pola regimen of the last patient (each cycle is 21 days)The safety of the therapeutic regimen measured by the major adverse events.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Source

Release
trials-2026-11-12-0.4.0
Release manifest SHA-256
0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
Registry capture
2026-11-12
Results copy, AACT
2026-03-23
NIH clinical studies file
2026-11-13

Source ClinicalTrials.gov

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07072208

GET https://conductscience.org/api/trials/v1/NCT07072208/registered