Trial · NCT07076095
A Phase II/III Study of IBB0979 in Combination With Topotecan Versus Topotecan in Relapsed Small Cell Lung Cancer
NCT07076095, Phase 2, Not yet recruiting, SUNHO（China）BioPharmaceutical CO., Ltd.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Phase II/III Study of IBB0979 in Combination With Topotecan Versus Topotecan in Relapsed Small Cell Lung Cancer. Trials, record NCT07076095. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07076095
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Phase II/III Study of IBB0979 in Combination With Topotecan Versus Topotecan in Relapsed Small Cell Lung Cancer
- NCT number
- NCT07076095
- Status
- Not yet recruiting
- Phases
- Phase 2
- Enrollment
- 200 participants, estimated
- Lead sponsor
- SUNHO（China）BioPharmaceutical CO., Ltd.
- Conditions
- Small Cell Lung Cancer
- Interventions
- IBB0979, topotecan hydrochloride for injection
- First posted
- 2025-07-21
- Last updated
- 2025-07-21
Source ClinicalTrials.gov
Registered outcomes23
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Frequency of adverse events (AEs) and SAEs (Phase II) | Approximately within 36 months | To investigate the safety characteristics. |
| Secondary | Pharmacokinetic (PK) Cmax (Phase II) | Approximately within 36 months | PK parameters (Cmax) following single dose. |
| Secondary | Pharmacokinetic (PK) Cmin (Phase II) | Approximately within 36 months | PK parameters (Cmin) following single dose. |
| Secondary | Pharmacokinetic (PK) Tmax (Phase II) | Approximately within 36 months | PK parameters (Tmax) following single dose. |
| Secondary | Pharmacokinetic (PK) AUC 0-t (Phase II) | Approximately within 36 months | PK parameters (AUC 0-t) following single dose. |
| Secondary | Pharmacokinetic (PK) AUC 0-∞ (Phase II) | Approximately within 36 months | PK parameters (AUC 0-∞) following single dose. |
| Secondary | Pharmacokinetic (PK) CL (Phase II) | Approximately within 36 months | PK parameters (CL) following single dose. |
| Secondary | Pharmacokinetic (PK) Vd (Phase II) | Approximately within 36 months | PK parameters (Vd) following single dose. |
| Secondary | Pharmacokinetic (PK) t1/2 (Phase II) | Approximately within 36 months | PK parameters (t1/2) following single dose. |
| Secondary | Pharmacokinetic (PK) λz (Phase II) | Approximately within 36 months | PK parameters (λz) following single dose. |
1 to 10 of 23Source ClinicalTrials.gov
See all 23 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07076095
GET https://conductscience.org/api/trials/v1/NCT07076095/registered?page=2