Trial · NCT07080229
Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery
NCT07080229, Phase 3, Recruiting, Suez Canal University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery. Trials, record NCT07080229. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07080229
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery
- NCT number
- NCT07080229
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 126 participants, estimated
- Lead sponsor
- Suez Canal University
- Conditions
- Cataract, Hypertension
- Interventions
- Intranasal dexmedetomidine, Intranasal normal saline
- First posted
- 2025-07-23
- Last updated
- 2026-04-07
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Mean arterial blood pressure (MAP) | From preoperative baseline until 2 hours postoperatively | Mean arterial blood pressure (MAP), measured in mmHg, will be recorded in both groups at the following time points: * Preoperative baseline * Every 5 minutes after intranasal drug administration * Intraoperative baseline * Immediately after peribulbar block * Every 5 minutes after the block until the end of the surgery * Every 15 minutes postoperatively until discharge |
| Secondary | Surgical cancellation rate | From the preoperative period until completion or cancellation of the surgery | The number and percentage of cases in each group in which cataract surgery will be cancelled due to uncontrolled blood pressure, inadequate sedation, patient anxiety, or any other reason |
| Secondary | Sedation score using the Modified Observer's Assessment of Alertness/Sedation Scale (MOAA/S). | From preoperative drug administration until 2 hours postoperatively | Sedation will be evaluated using the MOAA/S scale at predefined time points: * Every 5 minutes after intranasal drug administration * Intraoperative baseline * Immediately after peribulbar block * Every 5 minutes after the block until the end of the surgery * Every 15 minutes postoperatively until discharge The MOAA/S is a scale from 0 to 5 assessing a subject's responsiveness to verbal and physical stimuli as follows: 0: No response after painful stimuli 1. Responds only after painful trapezius squeeze 2. Responds only after mild prodding or shaking 3. Responds only after name is called loudly and/or repeatedly 4. Lethargic response to name spoken in normal tone 5. Responds readily to name spoken in normal tone |
| Secondary | Heart rate (HR) | From preoperative baseline until 2 hours postoperatively | Heart rate (HR) will be recorded in both groups at the following time points: * Preoperative baseline * Every 5 minutes after intranasal drug administration * Intraoperative baseline * Immediately after peribulbar block * Every 5 minutes after the block until the end of the surgery * Every 15 minutes postoperatively until discharge |
| Secondary | Patient Satisfaction | Assessed once the patient is in the post-anesthesia care unit (PACU) prior to discharge | Patient satisfaction with anesthesia care was measured using the Iowa Satisfaction with Anesthesia Scale (ISAS), a validated instrument specifically designed for monitored anesthesia care and sedation. The ISAS consists of 11 items rated on a 6-point Likert scale, with both positively and negatively worded statements. The total score was calculated as the mean of all items after appropriate reverse coding, with higher scores indicating greater satisfaction. |
| Secondary | Anesthesiologist Satisfaction | Assessed immediately after completion of the procedure | Anesthesiologist Satisfaction will be evaluated using structured 5 point Likert scale (1 = very dissatisfied, 5 = very satisfied). The assessment includes adequacy of sedation, ease of patient management, hemodynamic stability, airway safety, and overall satisfaction. A composite score will be calculated as the mean of all items, with higher scores indicating greater satisfaction. |
| Secondary | Surgeon Satisfaction | Assessed immediately after completion of the procedure | Surgeon satisfaction was assessed using a structured 5-point Likert scale (1 = very dissatisfied, 5 = very satisfied). The assessment included surgical field conditions, patient cooperation, ocular stability, ease of performing the procedure, and overall satisfaction. A composite score will be calculated as the mean of all items, with higher scores indicating greater satisfaction. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers6
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07080229
GET https://conductscience.org/api/trials/v1/NCT07080229/registered