Trial · NCT07085624
Early Optimization of Ceftazidime Regimen in Critical Care
NCT07085624, Not applicable, Not yet recruiting, Centre Hospitalier Universitaire de Saint Etienne
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Early Optimization of Ceftazidime Regimen in Critical Care. Trials, record NCT07085624. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07085624
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Early Optimization of Ceftazidime Regimen in Critical Care
- NCT number
- NCT07085624
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 128 participants, estimated
- Lead sponsor
- Centre Hospitalier Universitaire de Saint Etienne
- Conditions
- Infection in ICU, Sepsis, Septic Shock, Pseudomonas Aeruginosa Infection
- Interventions
- ceftazidime, plasma ceftazidime dosage
- First posted
- 2025-07-25
- Last updated
- 2026-09-16
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percentage of subjects with a ceftazidime concentration equal to or above the target concentration threshold (35 mg/L) at both 3h and 24h after the first administration, and below the toxicity threshold of 100 mg/L. | 24 hours | |
| Secondary | Patient severity assessed using the SOFA (Sequential Organ Failure Assessment Score) | day 7 | SOFA score from 0 to 24 The higher the score (24), the greater the incidence of organ failure |
| Secondary | death | day 28 | |
| Secondary | Occurrence of neurological adverse events defined as: seizure, myoclonus, encephalopathy or delirium, altered consciousness (Glasgow score) | day 28 | |
| Secondary | Occurrence of an overdose defined as a concentration greater than 100 mg/L. | day 28 | |
| Secondary | Renal function assessment | day 28 | creatinine clearance (mL/mn) with the CKD-EPI (Chronic Kidney Disease - Epidemiology Collaboration) equation |
| Secondary | Time to reach PK/PD (pharmacokinetics/pharmacodynamics) targets | 24 hours |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07085624
GET https://conductscience.org/api/trials/v1/NCT07085624/registered