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Trial · NCT07085806

To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery

NCT07085806, Not applicable, Recruiting, Institute of Liver and Biliary Sciences, India

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery. Trials, record NCT07085806. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07085806

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery
NCT number
NCT07085806
Status
Recruiting
Phases
Not applicable
Enrollment
60 participants, estimated
Lead sponsor
Institute of Liver and Biliary Sciences, India
Conditions
Liver Regeneration
Interventions
Pentoxifylline (also known as oxpentifylline), Plasmalyte
First posted
2025-07-25
Last updated
2025-07-25

Source ClinicalTrials.gov

Registered outcomes13

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryTo assess effect of Pentoxifylline supplementation on Anatomical (Volume) Regeneration of liver in the Perioperative period (POD-14) in Right lobe donor Hepatectomy2 weeks post-operativelyRegenerated liver volume post-surgery Day-14 and Percentage of volume restored after Post surgery day 14 as compared to pre-operatively calculated Remnaant liver volume
SecondaryTo evaluate the effect of Pentoxifylline on Serum Bilirubin- Time to Normalization2 weeksSerum bilirubin on Post-operative Day 1 to 7 and 14
SecondaryTo evaluate the effect on HGF1 weekHGF (Hepatocyte Growth Factor) levels on Baseline, Postoperative Day 3, and Day 7
SecondaryTo study the effect of Pentoxifylline supplementation on post-operative complications in donor right hepatectomyPostoperative Day 14Clavien-Dindo Classification Grading on Post-operative Day 14
SecondaryTime to normalziation of Aspartate TransaminasePost-operative Day 14Aspartate transaminase (Baseline, Post-operative Day 1 to 7 and 14)
SecondaryTime to normalzation of Alanine transaminasePost-operative Day 14Alanine Transaminase on BASELINE, POST-OPERATIVE DAY 1 TO 7 and 14
SecondaryTime to Normalisation of International Normalized RatioPost-operative Day 14International Normalized Ratio on Baseline Post-operative Day 1 to 7 and 14
SecondaryTime to normalisation of Serum Alkaline phosphatasePost-operative Day 14Serum Alkaline Phosphatase levels on Baseline, Post-operative Day 1 to 7 and 14
SecondaryTime to normalisation of Gamma-Glutamyl TransferasePost-operative Day 14Gamma-Glutamyl Transferase levels on baseline, Post-operative Day 1 to 7 and 14
SecondaryEffect on TNF-alpha (Tumor Necrosis Factor alpha)Post-operative Day 7TNF-alpha (Tumor Necrosis Factor alpha) levels on Baseline, Post-operative Day 3 and 7

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers3

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
16537374RESULTPubMed
21037437RESULTPubMed
22816029RESULTPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07085806

GET https://conductscience.org/api/trials/v1/NCT07085806/registered