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Trial · NCT07095933

The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy

NCT07095933, Early phase 1, Recruiting, Xuanwu Hospital, Beijing

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy. Trials, record NCT07095933. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07095933

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy
NCT number
NCT07095933
Status
Recruiting
Phases
Early phase 1
Enrollment
5 participants, estimated
Lead sponsor
Xuanwu Hospital, Beijing
Conditions
Epilepsy, Drug Resistant
Interventions
Everolimus
First posted
2025-07-31
Last updated
2026-04-07

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPercent Change From Baseline in Seizure Frequency Per 28 Daysassessed per 28 days during the treatment until the end of 12-week treatment.Percent change in 28-day frequency of seizures during the 12 week treatment and follow-up period relative to baseline
Secondary50% Seizure Responder RateBaseline observation period, and 12-week treatment period (ending at 12 weeks).The proportion of patients with a ≥ 50% reduction from Baseline in seizure frequency.
SecondarySeizure SeverityBaseline observation period, and 12-week treatment period (ending at 12 weeks).The percent change from baseline in seizure severity evaluated by Liverpool seizure severity scale (LSSS) .
SecondaryLife quality evaluationBaseline observation period, and 12-week treatment period (ending at 12 weeks).Percentage change from baseline in Quality of Life in Epilepsy-31 inventory (QOLIE-31) score.
SecondaryAdverse Eventsthrough study completion, 12 weeks.Rate of adverse events which were judged to be study-related throughout the study.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07095933

GET https://conductscience.org/api/trials/v1/NCT07095933/registered