Trial · NCT07116863
A Multicenter, Randomized, Double-Blind Phase 3 Trial of KDF1901 in Patients With Essential Hypertension
NCT07116863, Phase 3, Completed, Kyungdong Pharmaceutical Co., Ltd.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Multicenter, Randomized, Double-Blind Phase 3 Trial of KDF1901 in Patients With Essential Hypertension. Trials, record NCT07116863. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07116863
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Multicenter, Randomized, Double-Blind Phase 3 Trial of KDF1901 in Patients With Essential Hypertension
- NCT number
- NCT07116863
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 286 participants, actual
- Lead sponsor
- Kyungdong Pharmaceutical Co., Ltd.
- Conditions
- Essential Hypertension
- Interventions
- KDF1901-R0, KDF1901-L, KDF1901, KDF1901-R1
- First posted
- 2025-08-12
- Last updated
- 2025-08-12
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Mean Sitting Systolic Blood Pressure (MSSBP) from baseline to Week 8 | Baseline to Week 8 | Mean change in sitting systolic blood pressure (MSSBP) after 8 weeks of treatment, measured at trough using a validated automated device. |
| Secondary | Change in Mean Sitting Systolic Blood Pressure (MSSBP) from baseline to Week 8 | Baseline to Week 2 and Week 4 | Mean change in MSSBP after 2 and 4 weeks of treatment, compared to baseline. |
| Secondary | Change in Mean Sitting Diastolic Blood Pressure (MSDBP) from baseline to Week 2, Week 4, and Week 8 | Baseline to Week 2, Week 4, and Week 8 | Mean change in MSDBP measured at trough using an automated device. |
| Secondary | Proportion of subjects achieving target blood pressure at Weeks 2, 4, and 8 | Week 2, Week 4, and Week 8 | Proportion of subjects achieving MSSBP \<140 mmHg and MSDBP \<90 mmHg. For subjects with diabetes mellitus, target BP is MSSBP \<130 mmHg and MSDBP \<80 mmHg. |
| Secondary | Response rate at Weeks 2, 4, and 8 | Week 2, Week 4, and Week | Proportion of subjects who achieved a reduction of ≥20 mmHg in MSSBP or ≥10 mmHg in MSDBP from baseline. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 42259717 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07116863
GET https://conductscience.org/api/trials/v1/NCT07116863/registered