Trial · NCT07155369
UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases
NCT07155369, Not applicable, Active not recruiting, The Affiliated Hospital of Xuzhou Medical University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases. Trials, record NCT07155369. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07155369
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases
- NCT number
- NCT07155369
- Status
- Active not recruiting
- Phases
- Not applicable
- Enrollment
- 18 participants, estimated
- Lead sponsor
- The Affiliated Hospital of Xuzhou Medical University
- Conditions
- Systemic Lupus Erythematosus, Systemic Sclerosis
- Interventions
- UCAR-T cells, Cyclophosphamide, Fludarabine
- First posted
- 2025-09-04
- Last updated
- 2025-09-04
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | To evaluate the safety and tolerability of UCAR T-cell in participants with relapse/ refractory autoimmune diseases | 2 years | The incidence and severity of adverse events (AEs) |
| Primary | To evaluate the clinical responses and duration of UCAR-T cells in participants with relapse/ refractory autoimmune diseases | 2 years | Proportion of participants achieving SRI-4 response, change in the Systemic Lupus Erythematosus Disease Activity Index(SLEDAI) from baseline |
| Secondary | To characterize the cellular kinetics of UCAR T-cell in participants with relapse/ refractory autoimmune diseases | 2 years | AUC0-28d |
| Secondary | To characterize the cellular kinetics of UCAR T-cell in participants with relapse/ refractory autoimmune diseases | 2 years | Cmax |
| Secondary | To characterize the cellular kinetics of UCAR T-cell in participants with relapse/ refractory autoimmune diseases | 2 years | Tmax |
| Secondary | To characterize pharmacodynamics of of UCAR-T cells in participants. | 2 years | Changes in B-cell levels in the peripheral blood from baseline. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07155369
GET https://conductscience.org/api/trials/v1/NCT07155369/registered