Trial · NCT07164287
Retrospective Observational Study of Intensity Effects in Psychedelic-assisted Treatment
NCT07164287, Active not recruiting, University Hospital, Geneva
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Retrospective Observational Study of Intensity Effects in Psychedelic-assisted Treatment. Trials, record NCT07164287. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07164287
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Retrospective Observational Study of Intensity Effects in Psychedelic-assisted Treatment
- NCT number
- NCT07164287
- Status
- Active not recruiting
- Enrollment
- 376 participants, estimated
- Lead sponsor
- University Hospital, Geneva
- Conditions
- Major Depressive Disorder (MDD), Anxiety Disorders, Substance Use Disorder (SUD), PTSD - Post Traumatic Stress Disorder
- Interventions
- Lysergic Acid Diethylamide (LSD) or psilocybin
- First posted
- 2025-09-10
- Last updated
- 2025-10-02
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Self-reported depressive symptoms (BDI-II) | Baseline and 1 month after each psychedelic treatment session (sessions 1-3, up to 12 months) | Beck Depression Inventory-II, total scores ranging from 0 to 63, higher scores indicating higher depressive symptoms |
| Primary | Self-reported symptoms of anxiety (STAI) | Baseline and 1 month after each psychedelic treatment session (sessions 1-3, up to 12 months) | State-Trait Anxiety Inventory, total scores ranging from 20 to 80, higher scores indicating higher anxiety |
| Secondary | Self-reported intensity of mystical experience | the day of treatment administration | Assessed with the self-report Mystical experience Questionnaire (MEQ-30) with total man score ranging from 0 to 5, with higher scores indicating higher intensity of mystical experience |
| Secondary | heart rate | day of treatment administration | beats per minute |
| Secondary | Self-rated anxiety | day of treatment administration | Self-rated anxiety using a 0-100 visual analogue scale (VAS), with higher scores indicating higher anxiety |
| Secondary | Young Schema Questionnaire - Rasch version | Baseline (screening or preparation visit, before first psychedelic session), immediately after each psychedelic session (sessions 1-3, up to 9 months) and 1 month after each psychedelic session (sessions 1-3, up to 12 months after baseline) | 116-item self-report questionnaire assessing 20 early maladaptive schemas. Items are rated on a 6-point Likert scale (1 = completely untrue of me, 6 = describes me perfectly). Higher scores indicate greater schema intensity; schema-specific and overall mean scores can be derived. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07164287
GET https://conductscience.org/api/trials/v1/NCT07164287/registered