Trial · NCT07170475
A Phase Ib Trial of Combined Febuxostat and Inosine Therapy in Patients With Parkinson's Disease
NCT07170475, Phase 1, Recruiting, Fujita Health University
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. A Phase Ib Trial of Combined Febuxostat and Inosine Therapy in Patients With Parkinson's Disease. Trials, record NCT07170475. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07170475
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Phase Ib Trial of Combined Febuxostat and Inosine Therapy in Patients With Parkinson's Disease
- NCT number
- NCT07170475
- Status
- Recruiting
- Phases
- Phase 1
- Enrollment
- 24 participants, estimated
- Lead sponsor
- Fujita Health University
- Conditions
- Parkinson's Disease (PD)
- Interventions
- Febuxostat, Inosine
- First posted
- 2025-09-12
- Last updated
- 2025-09-12
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in plasma hypoxanthine concentration from baseline to Week 12 | 12 weeks | The difference in plasma hypoxanthine level (µmol/L) between pre-dose at Day 0 and Week 12 visit. |
| Secondary | Change in plasma hypoxanthine concentration from baseline to Week 4 | 4 weeks | The difference in plasma hypoxanthine level between pre-dose at Day 0 and Week 4 visit. |
| Secondary | Change in cerebrospinal fluid (CSF) hypoxanthine concentration from baseline to Week 12 | 12 weeks | The difference in CSF hypoxanthine level between the pre-dose at Day 0 and the Week 12 visit. |
| Secondary | Change in MDS-UPDRS Part III score from baseline to Week 12 | 12 weeks | The difference in Movement Disorder Society-Unified Parkinson's Disease Rating Scale motor examination (ON state) score between Day 0 and Week 12. |
| Secondary | Change in Mini-Mental State Examination (MMSE) score from baseline to Week 12 | 12 weeks | The difference in MMSE score between Day 0 and Week 12. |
| Secondary | Change in Geriatric Depression Scale-15 (GDS-15) score from baseline to Week 12 | 12 weeks | The difference in GDS-15 score between Day 0 and Week 12. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07170475
GET https://conductscience.org/api/trials/v1/NCT07170475/registered