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Trial · NCT07173127

Registered outcomes15

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange from baseline in the mean value of normalized activated protein C resistance (nAPCsr) at 3 months of treatment with RyeqoAt baseline and after 3 months of treatmentBlood dosage of normalized activated protein C resistance (nAPCsr)
SecondaryMean change from baseline to 3 months of treament in the value of sexual hormone-binding globulin (SHBG)At baseline and after 3 months of treatmentMean value of SHBG as expressed in nmol/l units
SecondaryMean change from baseline to 3 months of treament in the value of normalized thrombomodulin sensitivity ratios (nTMSR)At baseline and after 3 months of treatmentMean value of nTMSR as expressed as ratio
SecondaryMean change from baseline to 3 months of treament in the value of D-DimersAt baseline and after 3 months of treatmentMean value of D-dimers as expressed with ng/ml units
SecondaryMean change from baseline to 3 months of treament in the value of thrombin generation markersAt baseline and after 3 months of treatment
Mean value of thrombin generation markers, such as : thrombin generation markers * endogenous thrombin potential (ETP), expressed in nMxmin * peak value, expressed in nM * time to peak, expressed in min * lag time, expressed in min
SecondaryMean change from baseline to 3 months of treament in the value of antithrombin activityAt baseline and after 3 months of treatmentMean change in antithrombin activity, expressed as a percentage
SecondaryMean change from baseline to 3 months of treament in the value of Tissue factor pathway inhibitor (TFPI)At baseline and after 3 months of treatmentMean change in the value of TFPI, as expressed in ng/ml
SecondaryMean change from baseline to 3 months of treament in the value of fibrinogenAt baseline and after 3 months of treatmentMean change in the value of fibrinogen, as expressed in g/l
SecondaryMean change from baseline to 3 months of treament in the value of free protein SAt baseline and after 3 months of treatmentMean change in the value of free protein S, expressed as a percentage
SecondaryMean change from baseline to 3 months of treament in the value of factor VIII concentrationAt baseline and after 3 months of treatmentMean change in the value of factor VIII concentration, expressed as a percentage
SecondaryMean change from baseline to 3 months of treament in the value of thrombin-antithrombin-komplex (TAT)At baseline and after 3 months of treatmentMean change in the value of TAT concentration, expressed in microgr/l
OtherMean days of headache at 3 months of treatmentAt 3 months of treatmentNumber of participants having headache and, if so, mean numberof days spent experiencing headache
OtherMean number of days with pelvic pain at 3 months of treatmentAt 3 months of treatmentNumber of participants experiencing pelvic pain and, if so, mean number of days spent with pelvic pain
OtherMean difference from baseline on the Higham scale of bleeding at 3 months of treatmentAt baseline and after 3 months of treatmentThere is no minimum or maximum value. A score inferior to 100 indicates normal flow, a score of 100 or more suggests heavy bleeding, and a score of 150 or more signifies heavy bleeding
OtherMean number of days of experiencing hot flushAfter 3 months of treatmentNumber of participants experiecing hot flush and, if so, mean number of days spent experiecing hot flush

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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