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Trial · NCT07180563

Randomized Controlled Trial of Berberine in Combination With Doxycycline in the Treatment of Chronic Endometritis

NCT07180563, Phase 1, Phase 2, Recruiting, The Fourth Affiliated Hospital of Zhejiang University School of Medicine

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Randomized Controlled Trial of Berberine in Combination With Doxycycline in the Treatment of Chronic Endometritis. Trials, record NCT07180563. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07180563

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Randomized Controlled Trial of Berberine in Combination With Doxycycline in the Treatment of Chronic Endometritis
NCT number
NCT07180563
Status
Recruiting
Phases
Phase 1, Phase 2
Enrollment
206 participants, estimated
Lead sponsor
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Conditions
Chronic Endometritis
Interventions
Participants were treated with doxycycline + berberin for chronic endometritis (intervention group)., At present, the commonly used clinical treatment for chronic endometritis is oral doxycycline
First posted
2025-09-18
Last updated
2025-09-18

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
Primary
Patients in both groups started taking antibiotics after being diagnosed with chronic endometritis by CD138 testing. After a course of treatment, the conversion rate of chronic endometritis expression from positive to negative was compared between the tw
One month
SecondaryNumber of CD138 positives per 10 high-power fields; recurrence rate of uterine polyps; Number and size of recurrence of uterine polyps.One month

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers7

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
24462055RESULTPubMed
25385744RESULTPubMed
31926918RESULTPubMed
33501741RESULTPubMed
33663485RESULTPubMed
35621273RESULTPubMed
38358731RESULTPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07180563

GET https://conductscience.org/api/trials/v1/NCT07180563/registered