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Trial · NCT07186062

Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal Function

NCT07186062, Phase 4, Completed, Ain Shams University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal Function. Trials, record NCT07186062. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07186062

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal Function
NCT number
NCT07186062
Status
Completed
Phases
Phase 4
Enrollment
60 participants, actual
Lead sponsor
Ain Shams University
Conditions
Acute Decompensated Heart Failure (ADHF), Cardiorenal Syndrome (CRS)
Interventions
Levosimendan, Dobutamine, Milrinone
First posted
2025-09-22
Last updated
2026-09-21

Source ClinicalTrials.gov

Registered outcomes12

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
Primaryrenal function parameters.7 daysChanges in serum creatinine (mg/dl). Pre- and post-infusion values were compared to assess treatment response.
Primaryrenal function7 daysChanges in serum BUN (mg/dl). Pre- and post-infusion values were compared to assess treatment response.
Primaryrenal function7 daysChanges in eGFR (mL/min/1.73 m²). Pre- and post-infusion values were compared to assess treatment response.
Primaryrenal function7 daysChanges in urine output (mL/day). Pre- and post-infusion values were compared to assess treatment response.
Primarycardiac function7 dayschanges in ejection fraction % by transthoracic echocardiography. Pre- and post-infusion values were compared to assess treatment response.
Primarycardiac function7 daysChanges in cardiac index (L/min/m²) measured by EV1000 clinical platform device. Pre- and post-infusion values were compared to assess treatment response.
Primarycardiac function7 dayschanges in stroke volume variations (SVV) measured by EV1000 clinical platform. Pre- and post-infusion values were compared to assess treatment response.
Primarycardiac function7 dayschanges in systemic vascular resistance index (SVRI) using EV1000 clinical platform device. Pre- and post-infusion values were compared to assess treatment response.
Secondarymorbidity28 daylength of ICU stay (days).
Secondarymorbidity28 dayTotal hospital stay (days)

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07186062

GET https://conductscience.org/api/trials/v1/NCT07186062/registered