Trial · NCT07199946
A Phase I/II Trial to Preserve Residual Insulin Secretion in Children With Recent Onset Type 1 Diabetes by Giving Verapamil
NCT07199946, Phase 1, Phase 2, Recruiting, Johnny Ludvigsson
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Phase I/II Trial to Preserve Residual Insulin Secretion in Children With Recent Onset Type 1 Diabetes by Giving Verapamil. Trials, record NCT07199946. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07199946
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Phase I/II Trial to Preserve Residual Insulin Secretion in Children With Recent Onset Type 1 Diabetes by Giving Verapamil
- NCT number
- NCT07199946
- Status
- Recruiting
- Phases
- Phase 1, Phase 2
- Enrollment
- 36 participants, estimated
- Lead sponsor
- Johnny Ludvigsson
- Conditions
- Type 1 Diabetes
- Interventions
- Verapamil (Part A), Placebo
- First posted
- 2025-09-30
- Last updated
- 2025-09-30
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in C-peptide AUCmean 0-120 min) during an MMTT from baseline to month 24. | 24 months | |
| Primary | Number of participants with treatment-related adverse events as assessed by CTCAE v4.0". | 24 months | Adverse events are registered after history, clinical examinations, laboratory tests and ECG. Patients and parents are interviewed about tolerability |
| Secondary | Change in C-peptide fasting and 90 minute value during an MMTT from baseline to month 24 | 24 months | |
| Secondary | Proportion of patients with peak C-peptide > 0.20 nmol/l at month 24 | 24 months | |
| Secondary | Hemoglobin A1c (HbA1c), change between baseline and subsequent visits | 24 months | |
| Secondary | Insulin dose/kg body weight/24 hrs | 24 months |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07199946
GET https://conductscience.org/api/trials/v1/NCT07199946/registered