Trial · NCT07230886
Prospective Reduction Of Transplant Complications Through Enhanced Preservation Therapy to Prevent Primary Graft Dysfunction
NCT07230886, Not applicable, Recruiting, University Health Network, Toronto
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Prospective Reduction Of Transplant Complications Through Enhanced Preservation Therapy to Prevent Primary Graft Dysfunction. Trials, record NCT07230886. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07230886
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Prospective Reduction Of Transplant Complications Through Enhanced Preservation Therapy to Prevent Primary Graft Dysfunction
- NCT number
- NCT07230886
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 50 participants, estimated
- Lead sponsor
- University Health Network, Toronto
- Conditions
- Primary Graft Dysfunction
- Interventions
- Xo Port Organ Preservation System, Standard of Care - Ice packs
- First posted
- 2025-11-17
- Last updated
- 2026-07-13
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Primary Study Feasibility | 2.5 years | Determined by the mean number of participants recruited per month calculated on recruitment over 24 months. |
| Primary | Composite efficacy outcome of full-scare trial #1 | 2.5 years | 90-day mortality |
| Primary | Composite efficacy outcome of full-scare trial #2 | 2.5 years | severe PGD (defined through the ISHLT consensus definition need for MCS will be adjudicated in a blinded fashion with LVEF\<40% and CI\<2.0 on high dose inotropes |
| Primary | Composite efficacy outcome of full-scare trial #3 | 2.5 years | duration of mechanical ventilation |
| Primary | Composite efficacy outcome of full-scare trial #4 | 2.5 years | ICU length of stay (LOS) |
| Primary | Composite efficacy outcome of full-scare trial #5 | 2.5 years | index transplant LOS |
| Primary | Composite efficacy outcome of full-scare trial #6 | 2.5 years | Moderate to severe rejection based on ISHLT criteria at 90 days |
| Primary | Composite efficacy outcome of full-scare trial #7 | 2.5 years | change in EQ-5D-5L utility index score from baseline to 90 days with a clinically meaningful change defined as \>0.05 |
| Primary | Composite efficacy outcome of full-scare trial #8 | 2.5 years | cfDNA count measured over POD0, POD1, and POD7 |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07230886
GET https://conductscience.org/api/trials/v1/NCT07230886/registered