Effects of Resistance and Dual-Task Training on Physical, Oculomotor, and Executive Functions in Older Adults With MCI
NCT07278141, Not applicable, Not yet recruiting, Universidad Santo Tomas, Chile
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Effects of Resistance and Dual-Task Training on Physical, Oculomotor, and Executive Functions in Older Adults With MCI | ClinicalTrials.gov |
| NCT number | NCT07278141 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 66 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Universidad Santo Tomas, Chile | ClinicalTrials.gov |
| Conditions | Physical Function, Executive Function (Cognition), Saccadic Eye Movements | ClinicalTrials.gov |
| Interventions | Anaerobic therapeutic exercises (resistance exercise), Anaerobic therapeutic exercises (resistance exercise) plus Dual Task | ClinicalTrials.gov |
| First posted | 2025-12-11 | ClinicalTrials.gov |
| Last updated | 2025-12-11 | ClinicalTrials.gov |
Registered outcomes 12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Physical-functional condition - Risk of falls | Baseline, and immediately post-intervention (week 11), | The physical-functional condition, specifically the risk of falls of participants will be assessed using the Timed Up and Go Test (TUG). Description: Time in seconds required to stand up from a chair, walk three meters, turn, return, and sit down. Unit of Measure: Seconds (s) | ClinicalTrials.gov |
| Primary | Executive function - Inhibitory control | Baseline, and immediately post-intervention (week 11-12) | Participants' inhibitory control will be assessed using the Stroop Colour Test. Performance will be evaluated through response time. Unit of Measure: Milliseconds (ms) | ClinicalTrials.gov |
| Primary | Oculomotor Function- Saccadic and anti-saccadic oculomotor movement | Baseline, and immediately post-intervention (week 11) | Saccadic and anti-saccadic eye movements will be assessed using a non-invasive electrooculography (EOG) system (ADInstruments PTK15 EOG model and AD Instruments Brazil PowerLab T26-3079). Two surface electrodes will be placed at the outer canthi of the right and left eyes, with a ground electrode positioned on the forehead. Synchronization between target illumination and EOG signals will be controlled using LabChart software (version 7, Research Ltd.). Performance will be evaluated based on movement latency during visual tasks: left-to-right for saccadic movements and right-to-left for anti-saccadic movements. Unit of Measure: Milliseconds (ms). | ClinicalTrials.gov |
| Primary | Physical - functional condition - Physical function | Baseline, and immediately post-intervention (week 11) | The Physical-functional condition, specifically Participants' physical function will be assessed with the Short Physical Performance Battery (SPPB). Description: Composite score evaluating balance, gait speed, and lower limb strength. Unit of Measure: Points on a scale (0-12). | ClinicalTrials.gov |
| Primary | Physical - functional condition - Grip Strength | Baseline, and immediately post-intervention (week 11) | The Physical-functional condition, specifically the grip strenght of particiants will be assesment with the JAMAR dynamometer. Description: Maximum grip strength measured with a hydraulic dynamometer. Unit of Measure: Kilograms (kg) | ClinicalTrials.gov |
| Primary | Executive Function - Working Memory | Baseline, and immediately post-intervention (week 11-12) | Working memory will be assessed using the Corsi Block-Tapping Test (CBTT), administered in both forward and backward conditions. Performance will be evaluated based on response time for each condition. Unit of Measure: Milliseconds (ms) | ClinicalTrials.gov |
| Primary | Executive Function - Cognitive Flexibility | Baseline, and immediately post-intervention (week 11-12) | Cognitive flexibility will be assessed using the Trail Making Test (TMT). Performance will be evaluated through completion time for Part A (numbers only) and Part B (numbers and letters alternating). Unit of Measure: Miliseconds (ms). | ClinicalTrials.gov |
| Secondary | Sociodemographic variable - Age | Baseline | Age of participants recorded during the first meeting. Unit of Measure: Years | ClinicalTrials.gov |
| Secondary | Sociodemographic variable - Sex | Baseline | Sex of participants recorded during the first meeting. Unit of Measure: Male/Female (categorical variable). | ClinicalTrials.gov |
| Secondary | Sociodemographic variables-Educational Level | Baseline | Highest educational level attained by participants. Unit of Measure: Categorical variable (e.g., primary, secondary, higher education). | ClinicalTrials.gov |
| Secondary | Health indicators- Comorbidities | Baseline | Presence of comorbidities such as hypertension, diabetes, or hypercholesterolemia, collected through validated questionnaires. Unit of Measure: Presence/absence (binary categorical variable). | ClinicalTrials.gov |
| Secondary | Anthropometric variable- Body Mass Index (BMI) | Baseline | BMI calculated according to WHO protocols as weight (kg) divided by height squared (m²). Unit of Measure: kg/m² | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 4
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 4
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Corsi Block-Tapping Test | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Trail Making Test A | Primary outcome | ConductCognition |
| Trail Making Test B | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)