Trial · NCT07281586
Step-down Therapy After Long-term Osteoporosis Treatment
NCT07281586, Phase 4, Recruiting, National Taiwan University Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Step-down Therapy After Long-term Osteoporosis Treatment. Trials, record NCT07281586. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07281586
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Step-down Therapy After Long-term Osteoporosis Treatment
- NCT number
- NCT07281586
- Status
- Recruiting
- Phases
- Phase 4
- Enrollment
- 44 participants, estimated
- Lead sponsor
- National Taiwan University Hospital
- Conditions
- Osteoporosis
- Interventions
- zoledronate, zoledronate, Denosumab De-escalation
- First posted
- 2025-12-15
- Last updated
- 2025-12-15
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Lumbar Spine BMD Over 2 Years | 2 Years | Change in Lumbar Spine BMD Over 2 Years |
| Secondary | Change in Total hip BMD Over 2 Years | 2 Years | Change in Total hip BMD Over 2 Years |
| Secondary | Change in Femoral Neck BMD Over 2 Years | 2 Years | Change in Femoral Neck BMD Over 2 Years |
| Secondary | Change in C-terminal telopeptide Over 2 Years | 2 Years | Change in C-terminal telopeptide over 2 years, which reflects the level of bone resorption, will be used to assess how bone turnover responds to the intervention throughout the study period. |
| Secondary | Change in Procollagen Type I N-Propeptide Over 2 Years | 2 Years | Change in Procollagen Type I N-Propeptide over 2 years, which reflects the level of bone formation, will be used to assess how bone turnover responds to the intervention throughout the study period. |
| Secondary | Incidence of clinical osteoporotic fracture | 2 years | Incidence of clinical osteoporotic fracture |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07281586
GET https://conductscience.org/api/trials/v1/NCT07281586/registered