Trial · NCT07347977
Lidocaine Decreases Postoperative Lung Cancer Reoccurance and Metatasis Risk
NCT07347977, Not applicable, Not yet recruiting, First Affiliated Hospital of Ningbo University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Lidocaine Decreases Postoperative Lung Cancer Reoccurance and Metatasis Risk. Trials, record NCT07347977. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07347977
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Lidocaine Decreases Postoperative Lung Cancer Reoccurance and Metatasis Risk
- NCT number
- NCT07347977
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 1,400 participants, estimated
- Lead sponsor
- First Affiliated Hospital of Ningbo University
- Conditions
- Non-Small Cell Lung Cancer, Recurrence, Survival Analysis
- Interventions
- Lidocaine (drug)
- First posted
- 2026-01-16
- Last updated
- 2026-01-16
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Disease-Free Survival (DFS) | Up to 36 months after operation | DFS is defined as the time from the date of surgery to the first documentation of disease recurrence (including local recurrence, regional lymph node metastasis, or distant metastasis) or death from any cause. |
| Secondary | Overall Survival (OS) | 36month after operation | Overall survival is defined as the time from randomization to death from any cause |
| Secondary | EuroQol 5-Dimension 5-Level Questionnaire (EQ-5D-5L) | Baseline, Postoperative Day 1, Day 3, Discharge, and at 6, 12, 18, 24, 36 months post-surgery | The EQ-5D-5L is used to assess health-related quality of life across five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. The EQ-5D-5L index score is calculated using population-based preference weights and typically ranges from less than 0 (health states worse than death) to 1 (full health), with higher scores indicating better health-related quality of life.In addition, the EQ Visual Analogue Scale (EQ-VAS) records the participant's self-rated health on a vertical scale ranging from 0 (worst imaginable health) to 100 (best imaginable health), with higher scores indicating better perceived health. |
| Secondary | Cancer-specific quality of life measured using the Functional Assessment of Cancer Therapy - Lung (FACT-L) | Baseline, Postoperative Day 1, Day 3, Discharge, and at 6, 12, 18, 24, 36 months post-surgery | The FACT-L is a validated instrument that includes the Functional Assessment of Cancer Therapy - General (FACT-G) and a lung cancer-specific subscale. The total FACT-L score ranges from 0 to 136, with higher scores indicating better cancer-specific quality of life. |
| Other | Total length of hospital stay | Up to 36 months | Total length of hospital stay, including readmission, up to 36 months |
| Other | Changes in Serum Biomarkers | Baseline, postoperative Day 1, postoperative Day 3, and at hospital discharge (assessed up to 5 days postoperatively). | Changes in pro-inflammatory cytokine levels (e.g., interleukin-6 \[IL-6\], tumor necrosis factor-alpha \[TNF-α\], matrix metalloproteinase-9 \[MMP-9\], and matrix metalloproteinase-2 \[MMP-2\]) from baseline. |
| Other | Incidence of Perioperative Adverse Events and Pain Scores | From the end of surgery up to hospital discharge (approximately 7-10 days) | Assessment of perioperative complications including nausea, vomiting, and delirium, as well as pain intensity assessed using the Visual Analog Scale (VAS) ranging from 0 (no pain) to 10 (worst imaginable pain), with higher scores indicating greater pain intensity. |
| Other | Incidence of Cardiovascular Events | At 6 months and 12 months post-surgery | Documentation of any new-onset cardiovascular events (e.g., arrhythmia, myocardial infarction) occurring after treatment. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers12
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07347977
GET https://conductscience.org/api/trials/v1/NCT07347977/registered