Trial · NCT07355712
Combined Effect of Prolotherapy and Personalized Physical Activity on Knee Osteoarthritis Progression
NCT07355712, Not applicable, Completed, Gadjah Mada University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Combined Effect of Prolotherapy and Personalized Physical Activity on Knee Osteoarthritis Progression. Trials, record NCT07355712. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07355712
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Combined Effect of Prolotherapy and Personalized Physical Activity on Knee Osteoarthritis Progression
- NCT number
- NCT07355712
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 74 participants, actual
- Lead sponsor
- Gadjah Mada University
- Conditions
- Prolotherapy
- Interventions
- Prolotherapy Only, Prolotherapy, Personalized Physical Activity Program
- First posted
- 2026-01-21
- Last updated
- 2026-01-21
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pain and Functional Capacity | 6 week | The primary outcome measure for this study is pain dan functional capacity using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) WOMAC Questionnaire consist of 3 subscales (pain, stiffness, and physical function). Pain subscale can be scored between 0-20 points, stiffness subscale can be scored between 0-8 points, and physical function subscales can be scored between 0-68 points. Those points can be interpreted better if its low and worser if it high in total (0-24 points for mild, 25-48 points for moderate, and 49-72 points for severe) |
| Secondary | Concentration of IL-1 Beta and MMP-3 | 6 week | Biomarker such IL-1 Beta and MMP-3 were measured by ELISA using kits from ABclonal (Cat. No. RK00001, Lot No. 9680034260724 for IL-1 Beta) and (Cat. No. RK00001, Lot No. 9680034260724 for MMP-3) |
| Secondary | Pain with Visual Analog Scale | 6 weeks | VAS Questionnaire points will be between 0 (no pain) and 100 (severe intolerable pain) |
| Secondary | Quality of Life with EQ-5D-5L | 6 weeks | EQ-5D-5L Indonesian value set will have 5 segments (mobility, looking after myself, doing usual activities, pain and discomfort, feeling worried, sad, or unhappy), each segments will have 0-5 points The points can be interpret as if the higher the points, the better quality of life will be |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07355712
GET https://conductscience.org/api/trials/v1/NCT07355712/registered