Trial · NCT07372040
Add-on Diuretics in Acute Decompensated Heart Failure
NCT07372040, Phase 2, Recruiting, Tanta University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Add-on Diuretics in Acute Decompensated Heart Failure. Trials, record NCT07372040. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07372040
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Add-on Diuretics in Acute Decompensated Heart Failure
- NCT number
- NCT07372040
- Status
- Recruiting
- Phases
- Phase 2
- Enrollment
- 66 participants, estimated
- Lead sponsor
- Tanta University
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- empagliflozin, Acetazolamide, metolazone
- First posted
- 2026-01-28
- Last updated
- 2026-02-04
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The cumulative urine output measured over 3 days | 3 days | |
| Secondary | - The change in serum level of N-terminal pro-brain natriuretic peptide (NT-proBNP) | 4 days | Blood samples will be collected at baseline and after 4 days |
| Secondary | The change in serum level of Soluble suppression of tumorigenicity 2 (sST2) | 4 days | Blood samples will be collected at baseline and after 4 days |
| Secondary | The change in urinary level of Tissue inhibitor of metalloproteinases-2 (TIMP-2 ) | 3 days | Urine samples will be collected at baseline and after 3 days |
| Secondary | The change in urinary level of Insulin-like growth factor-binding protein 7 (IGFBP7) | 3 days | Urine samples will be collected at baseline and after 3 days |
| Secondary | 30-day mortality | up to 30 days | Proportion of patients who die within 30 days of randomization |
| Secondary | Proportion of patients achieving an ADVOR Score ≤ 1 without the need for escalating diuretic strategy | 3 days | the treating physician will calculate the congestion score, on a scale from 0 to 10 on the basis of the sum of scores for the degree of edema (0 to 4), pleural effusion (0 to 3), and ascites (0 to 3), with higher scores indicating a worse condition on all scales |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07372040
GET https://conductscience.org/api/trials/v1/NCT07372040/registered