Trial · NCT07379047
Efficacy and Safety of NB003 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
NCT07379047, Phase 2, Phase 3, Recruiting, Ningbo Newbay Technology Development Co., Ltd
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy and Safety of NB003 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST). Trials, record NCT07379047. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07379047
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy and Safety of NB003 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
- NCT number
- NCT07379047
- Status
- Recruiting
- Phases
- Phase 2, Phase 3
- Enrollment
- 255 participants, estimated
- Lead sponsor
- Ningbo Newbay Technology Development Co., Ltd
- Conditions
- GIST - Gastrointestinal Stromal Tumor, Advanced
- Interventions
- NB003, regorafenib
- First posted
- 2026-01-30
- Last updated
- 2026-11-12
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Progression-free Survival (PFS) | From randomization until database cut-off, approximately 28 months | for part 1 |
| Primary | Objective response rate (ORR) | approximately 24 months since the first subject enrolled | for part 2 |
| Secondary | Objective response rate (ORR) | From randomization until database cut-off, approximately 28 months | for part 1 |
| Secondary | Progression-free survival (PFS) | approximately 24 months since the first subject enrolled | for part 2 |
| Secondary | Duration of Response(DOR) | approximately 24 months since the first subject enrolled | for part 2 |
| Secondary | Duration of Response(DOR) | approximately 28 months since the first subject enrolled | for part 1 |
| Secondary | Overall Survival(OS) | approximately 24-36 months | for part 1 |
| Secondary | Disease Control Rate (DCR) | Approximately 28 months since first subject enrolled | for part 1 |
| Secondary | Overall Survival(OS) | approximately 24-36 months | for part 2 |
| Secondary | Disease Control Rate (DCR) | Approximately 24 months since first subject enrolled | for part 2 |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07379047
GET https://conductscience.org/api/trials/v1/NCT07379047/registered