Trial · NCT07380841
Metformin vs Inositol vs Diet vs Combination Therapy in PCOS
NCT07380841, Not applicable, Completed, Islamabad Medical and Dental College
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Metformin vs Inositol vs Diet vs Combination Therapy in PCOS. Trials, record NCT07380841. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07380841
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Metformin vs Inositol vs Diet vs Combination Therapy in PCOS
- NCT number
- NCT07380841
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 192 participants, actual
- Lead sponsor
- Islamabad Medical and Dental College
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Metabolic Syndrome
- Interventions
- Metformin Hydrochloride, Myo-Inositol, Dietary Restriction, Metformin + Myo-inositol + Dietary Restriction
- First posted
- 2026-02-02
- Last updated
- 2026-02-02
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in insulin resistance (HOMA-IR) | Baseline to 12 weeks | Mean change in insulin resistance as measured by the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), calculated from fasting plasma glucose and fasting serum insulin levels, comparing baseline values to 12-week follow-up among the four treatment groups (metformin, inositol, dietary restriction, and combination therapy). |
| Secondary | Change in body weight and body mass index (BMI) | Baseline to 12 weeks | Mean change in body weight (kg) and body mass index (kg/m²) from baseline to 12 weeks. |
| Secondary | Change in menstrual cycle regularity | Baseline to 12 weeks | Proportion of participants achieving regular menstrual cycles or improvement in cycle regularity over the 12-week intervention period.Baseline to 12 weeks |
| Secondary | Change in serum androgen levels | Baseline to 12 weeks | Mean change in serum total testosterone levels from baseline to 12 weeks |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 42517336 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07380841
GET https://conductscience.org/api/trials/v1/NCT07380841/registered