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Trial · NCT07391709

Investigation of the Protective Effect of Alpha Lipoic Acid on Ischemic Reperfusion Damage in Ischemic Priapism in Rats

NCT07391709, Not applicable, Completed, Trabzon Kanuni Education and Research Hospital

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Investigation of the Protective Effect of Alpha Lipoic Acid on Ischemic Reperfusion Damage in Ischemic Priapism in Rats. Trials, record NCT07391709. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07391709

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Investigation of the Protective Effect of Alpha Lipoic Acid on Ischemic Reperfusion Damage in Ischemic Priapism in Rats
NCT number
NCT07391709
Status
Completed
Phases
Not applicable
Enrollment
18 participants, actual
Lead sponsor
Trabzon Kanuni Education and Research Hospital
Conditions
Priapism, Reperfusion Injury
Interventions
Ischemic priapism + reperfusion, Ischemic priapism + reperfusion + ALA, Ischemic priapism + reperfusion + ALA
First posted
2026-02-06
Last updated
2026-02-06

Source ClinicalTrials.gov

Registered outcomes9

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in serum total antioxidant status (TAS) measured by Erel spectrophotometric assay7 days after reperfusionSerum total antioxidant status (TAS) will be measured using the Erel spectrophotometric assay.Unit of Measure mmol Trolox equivalent/L
PrimaryChange in serum total oxidant status (TOS) measured by Erel spectrophotometric assay7 days after reperfusionSerum total oxidant status (TOS) will be measured using the Erel spectrophotometric assay.Unit of Measure µmol H₂O₂ equivalent/L
PrimaryChange in serum glutathione peroxidase (GPx) activity measured by spectrophotometric enzyme activity assay7 days after reperfusionSerum glutathione peroxidase (GPx) activity will be measured using a spectrophotometric enzyme activity assay.Unit of Measure U/L
PrimaryChange in serum malondialdehyde (MDA) concentration measured by ELISA7 days after reperfusionSerum malondialdehyde (MDA) concentration will be measured using a commercial ELISA kit.Unit of Measure ng/mL
PrimaryChange in serum ischemia-modified albumin (IMA) concentration measured by ELISA7 days after reperfusionSerum ischemia-modified albumin (IMA) concentration will be measured using a commercial ELISA kit.Unit of Measure U/mL
SecondaryChange in serum tumor necrosis factor-alpha (TNF-α) concentration measured by ELISA7 days after reperfusionSerum tumor necrosis factor-alpha (TNF-α) concentration will be measured using a commercial ELISA kit.Unit of Measure pg/mL
SecondaryChange in penile tissue tumor necrosis factor-alpha (TNF-α) concentration measured by ELISA7 days after reperfusionPenile tissue tumor necrosis factor-alpha (TNF-α) concentration will be measured using a commercial ELISA kit and normalized to tissue protein content.Unit of Measure pg/mg protein
OtherChange in GRP78 protein expression in penile tissue measured by immunohistochemistry7 days after reperfusionGRP78 protein expression in penile tissue will be assessed using immunohistochemical semi-quantitative scoring.Unit of Measure Semi-quantitative score
OtherChange in CHOP protein expression in penile tissue measured by immunohistochemistry7 days after reperfusionCHOP protein expression in penile tissue will be assessed using immunohistochemical semi-quantitative scoring.Unit of Measure Semi-quantitative score

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07391709

GET https://conductscience.org/api/trials/v1/NCT07391709/registered