Trial · NCT07393373
Open-Label, Long-Term, Extension Study of Infigratinib in Children With Hypochondroplasia
NCT07393373, Phase 2, Enrolling by invitation, QED Therapeutics, a BridgeBio company
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Open-Label, Long-Term, Extension Study of Infigratinib in Children With Hypochondroplasia. Trials, record NCT07393373. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07393373
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Open-Label, Long-Term, Extension Study of Infigratinib in Children With Hypochondroplasia
- NCT number
- NCT07393373
- Status
- Enrolling by invitation
- Phases
- Phase 2
- Enrollment
- 135 participants, estimated
- Lead sponsor
- QED Therapeutics, a BridgeBio company
- Conditions
- Hypochondroplasia
- Interventions
- Infigratinib
- First posted
- 2026-02-06
- Last updated
- 2026-08-26
Source ClinicalTrials.gov
Registered outcomes19
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Incidence of treatment emergent adverse events (TEAE) and serious TEAE | 10 years | |
| Primary | Changes over time in standing height Z-score in relation to HCH and non-HCH growth charts | 10 years | |
| Secondary | Changes over time in AHV Z-score | 10 years | |
| Secondary | Changes over time in body proportions | 10 years | |
| Secondary | Changes over time in weight Z-score | 10 years | |
| Secondary | Changes overtime in BMI | 10 years | |
| Secondary | Age of puberty onset and time to Tanner stage ≥4 | 10 years | |
| Secondary | Changes over time in body composition as assessed by DXA (dual x-ray absorptiometry) scans | 10 years | |
| Secondary | Changes over time in bone morphology/density by x-ray and DXA | 10 years | |
| Secondary | Change in psychomotor function assessed by age-appropriate computerized tests (Detection Test) | 10 years |
1 to 10 of 19Source ClinicalTrials.gov
See all 19 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests1
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as |
|---|---|
| 1-Back Task | Secondary outcome |
Source ConductCognition
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07393373
GET https://conductscience.org/api/trials/v1/NCT07393373/registered