Trial · NCT07398404
A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
NCT07398404, Phase 1, Phase 2, Not yet recruiting, Medical University of South Carolina
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients. Trials, record NCT07398404. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07398404
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
- NCT number
- NCT07398404
- Status
- Not yet recruiting
- Phases
- Phase 1, Phase 2
- Enrollment
- 64 participants, estimated
- Lead sponsor
- Medical University of South Carolina
- Conditions
- Obesity, Smoking Cessation, Bariatric Surgery Patients
- Interventions
- Naltrexone hydrochloride, Bupropion Hydrochloride Extended-release, Cognitive-Behavioral Therapy
- First posted
- 2026-02-09
- Last updated
- 2026-07-08
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Study enrollment to assess Feasibility | 16 weeks | Number of participants enrolled out of participants screened. |
| Primary | Mean number treatment sessions attended to assess Feasibility | 16 weeks | Mean number of treatment sessions attended. |
| Primary | Retention to assess Feasibility | 16 weeks | Retention will be measured as the percent of participants that attend the post treatment assessment. |
| Primary | Treatment credibility to assess Acceptability | Week 4, Week 8, Week 12, Week 16 | Treatment credibility will be assessed via self-report monthly. Acceptability measured as the percent of participants that agree the intervention is acceptable (0-100%, with higher scores being indicative of higher treatment credibility). |
| Primary | Treatment satisfaction to assess Acceptability | Week 16 | Treatment satisfaction will be assessed via self-report at post-treatment. Acceptability measured as the percent of participants that agree the intervention is satisfactory (0-100%, with higher scores being indicative of higher treatment satisfaction). |
| Primary | Percent weight change | Baseline, Week 16, 6-month follow-up | Percent weight change will be calculated from baseline to post-treatment, and post-treatment to 6-month follow-up. |
| Primary | Smoking cessation, as measured by exhaled carbon monoxide | Baseline, Week 4, Week 8, Week 12, Week 16, 6-month follow-up | Smoking cessation will be evaluated biochemically, through mean exhaled carbon monoxide concentration. |
| Primary | Smoking cessation, as measured by timeline followback interview | Baseline, Week 4, Week 8, Week 12, Week 16, 6-month follow-up | Smoking cessation will be evaluated behaviorally, through point prevalence abstinence data obtained by timeline followback interviews. |
| Secondary | Nicotine dependence, as measured by the Fagerstrom Test for Nicotine Dependence | Baseline, Week 16, 6-month follow-up | The Fagerstrom Test for Nicotine Dependence is a self-report measure that classifies level of nicotine dependence. Participants respond to a series of questions assessing time of first cigarette after waking, difficulty refraining from smoking in places where smoking is prohibited, and frequency of smoking. Total score range 0-10 with higher scores indication more nicotine dependence. |
| Secondary | Depressive symptomatology, as measured by the Patient Health Questionnaire-9 | Baseline, Week 16, 6-month follow-up | The Patient Health Questionnaire-9 is a brief, psychometrically sound, and widely used self-report measure of depression in diverse medical settings. The total score on the PHQ-9 ranges from 0 to 27, with higher scores indicating greater severity of depressive symptoms. |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 32524412 | BACKGROUND |
Source PubMed
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| K23DA064898 | A Multiple Health Behavior Change Intervention for Weight-Loss and Smoking Cessation among Pre-Bariatric Surgery Patients | Smith, Caitlin | YALE UNIVERSITY | NATIONAL INSTITUTE ON DRUG ABUSE | 2026 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07398404
GET https://conductscience.org/api/trials/v1/NCT07398404/registered