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Trial · NCT07403604

Registered outcomes12

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryHepatic de novo lipogenesis (absolute values)Study Days 8 and 16Percent incorporation of newly synthesized fatty acids into serum or very low-density lipoprotein (VLDL) triglyceride (TG) (units: %)
PrimaryHepatic de novo lipogenesis (relative/change)Study Days 8 and 16Percent incorporation of newly synthesized fatty acids into serum or VLDL TG (units: fold difference and/or ∆%)
SecondaryFasting plasma/serum insulin (absolute values)Study Days 8 and 16Measurement of fasting endogenous insulin levels during treatment with diazoxide 2 mpk vs. placebo (units: micro-international units \[µIU\] per mL).
SecondaryFasting plasma/serum insulin (relative/change)Study Days 8 and 16Measurement of fasting endogenous insulin levels during treatment with diazoxide 2 mpk vs. placebo (units: fold difference and/or change in µIU/mL).
SecondaryFasting plasma glucoseStudy Days 8 and 16Measurement of fasting plasma glucose levels during treatment with diazoxide 2 mpk vs. placebo (units: mg/dL).
SecondaryFasting serum or plasma triglyceridesStudy Days 8 and 16Measurement of fasting plasma or serum triglyceride levels during treatment with diazoxide 2 mpk vs. placebo (units: mg/dL).
SecondaryFasting plasma free fatty acidsStudy Days 8 and 16Measurement of fasting plasma free fatty acid levels during treatment with diazoxide 2 mpk vs. placebo (units: mmol/L).
SecondarySteady state plasma glucose (SSPG) during ISTAt time points of 150, 160, 170, and 180 minutes during each 3-hour IST protocolMeasurement of plasma glucose at 10-minute intervals during 30-minute steady-state period at the end of each IST (units: mg/dL)
OtherSkin de novo lipogenesis3 hoursPercent incorporation of newly synthesized fatty acids into sebum from healthy skin and, if present, skin from inflammatory skin lesions (units: %)
OtherDeuterium tracer enrichment in body water (measured in blood)Study Days 8 and 16Enrichment of total body water with deuterated water (2H2O/D2O) (units: %)
OtherDeuterium tracer enrichment in body water (measured in saliva)Study Days 8 and 16Enrichment of total body water with deuterated water (2H2O/D2O) (units: %)
OtherDeuterium tracer enrichment in sebum3 hoursEnrichment of sebum with deuterated water (2H2O/D2O) (units: %)

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT07403604/registered