Sleep, Dreaming, and Virtual Reality for Mental Health
NCT07408206, Early phase 1, Recruiting, Northwestern University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Sleep, Dreaming, and Virtual Reality for Mental Health | ClinicalTrials.gov |
| NCT number | NCT07408206 | ClinicalTrials.gov |
| Status | Recruiting | ClinicalTrials.gov |
| Phases | Early phase 1 | ClinicalTrials.gov |
| Enrollment | 70 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Northwestern University | ClinicalTrials.gov |
| Conditions | Anxiety | ClinicalTrials.gov |
| Interventions | Dream Yoga Inspired Intervention, Sleep Health Enhancement Program (SHEP) | ClinicalTrials.gov |
| First posted | 2026-02-13 | ClinicalTrials.gov |
| Last updated | 2026-10-16 | ClinicalTrials.gov |
Registered outcomes 12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Changes in frontal midline theta | Baseline to 8 weeks | The intervention will preferentially increase frontal midline theta during a short period of breath meditation (one recording session before and one after the intervention); EEG power band-passed at 4-10 Hz will be quantified and related to findings on self-referential processing (Nondual Awareness Dimensional Assessment) | ClinicalTrials.gov |
| Primary | Changes in Sleep Architecture | Baseline and 8 weeks | Sleep architecture will be compared with regard to time spent in each sleep stage, microarousals, slow-wave power, sleep spindles, and coupling between slow waves and spindles. Spectral power differences in different sleep stages. | ClinicalTrials.gov |
| Secondary | Changes in Lucid Dreaming Frequency | Baseline to 8 weeks | Lucidity will be assessed with a composite of questionnaires at week 1 and measuring changes at week 8 and using self-reports of lucid dreams recorded in daily dream journals and/or nightly reports during the 7-week intervention.Additionally participants will fill tge Self-report Questionnaires: 1. Lucid Dreaming Skills Questionnaire (LUSK) 2. Lucid Dream Control-Specific Experiences (LDC-SE) | ClinicalTrials.gov |
| Secondary | Changes in Cognitive Flexibility - Cognitive Flexibility Scale | Baseline to 8 weeks | Several facets of cognitive flexibility will be measured with the Cognitive Flexibility Scale | ClinicalTrials.gov |
| Secondary | Changes in Cognitive Flexibility - Probabilistic Reversal | Baseline to 8 weeks | Several facets of cognitive flexibility will be measured with several standard neuropsychological tests such as the Probabilistic Reversal Learning. | ClinicalTrials.gov |
| Secondary | Changes in Cognitive Flexibility - Stroop Test | Baseline to 8 weeks | Several facets of cognitive flexibility will be measured with standard neuropsychological tests such as the Stroop color-word test, Emotional Stroop. | ClinicalTrials.gov |
| Other | Change in PROMIS Anxiety Questionnaire Score | baseline to 8 weeks | The Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety Questionnaire is a self-report measure assessing anxiety symptoms. It generates a T-score standardized to the general U.S. population (mean = 50, SD = 10). Higher scores indicate more severe anxiety symptoms. | ClinicalTrials.gov |
| Other | Change in Self-referential Processing | Baseline to 8 week | Self-referential processing will be assessed using a composite of subjective and neurophysiological measures. Subjective measures include the Mindful Attention Awareness Scale (MAAS), the Cognitive and Affective Mindfulness Scale-Revised (CAMS-R), and the Nondual Awareness Dimensional Assessment (NADA) and Beck Cognitive Insight Scale. A composite score may be computed via z-score standardization. A composite score may be computed via z-score standardization or used in exploratory correlation analyses. Higher mindfulness and nondual awareness scores, together with increased frontal midline theta, will be interpreted as indicators of enhanced self-referential regulation. | ClinicalTrials.gov |
| Other | Changes in Markers of Inflammation | Baseline to 8 weeks | Circulating markers of inflammation will be measured via a finger blood prick and changes will be quantified before and after the intervention. | ClinicalTrials.gov |
| Other | Changes in cellular aeging and oxidative stress | Baseline and 8 weeks | Circulating markers of ageing and oxidative stress will be measured via a finger blood prick and changes will be quantified before and after the intervention. | ClinicalTrials.gov |
| Other | Changes in Creativity - Alternate Uses Task | Baseline to 8 weeks | Several facets of Creativitywill be measured with the Remote Association Task. | ClinicalTrials.gov |
| Other | Changes in Creativity - Remote Associates Task | Baseline to 8 weeks | Several facets of creativity will be measured with the Remote Association Task. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 5
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Alternative Uses Task | Other outcome | ConductCognition |
| Emotional Stroop Task | Secondary outcome | ConductCognition |
| Probabilistic Reversal Learning | Secondary outcome | ConductCognition |
| Remote Associates Test | Other outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)