Trial · NCT07420894
Comparison of Combination of Itraconazole and Isotretinoin Versus Itraconazole Alone in the Treatment of Resistant Trichophyton Infection
NCT07420894, Not applicable, Completed, Multan Medical And Dental College
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparison of Combination of Itraconazole and Isotretinoin Versus Itraconazole Alone in the Treatment of Resistant Trichophyton Infection. Trials, record NCT07420894. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07420894
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparison of Combination of Itraconazole and Isotretinoin Versus Itraconazole Alone in the Treatment of Resistant Trichophyton Infection
- NCT number
- NCT07420894
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 148 participants, actual
- Lead sponsor
- Multan Medical And Dental College
- Conditions
- Dermatophytosis, Trichophyton Infection, Resistant Dermatophyte Infection
- Interventions
- Itraconazole + Isotretinoin, Itraconazole (ITZ)
- First posted
- 2026-02-19
- Last updated
- 2026-02-19
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Clinical cure | Up to 8 weeks | Proportion of participants with complete resolution of clinical signs and symptoms of dermatophytosis, defined as absence of active erythema, scaling, pruritus, and advancing lesion margin on clinical examination using a structured assessment proforma. |
| Primary | Mycological cure | up to 8 weeks | Proportion of participants with negative potassium hydroxide microscopy from the previously involved site at the end of treatment. Where culture is performed at follow-up, mycological cure additionally requires negative fungal culture. |
| Secondary | Time to symptom resolution | Up to 8 weeks | Number of days from initiation of treatment to complete disappearance of pruritus and cessation of lesion expansion, documented on follow-up assessment and or participant diary, and confirmed on clinical review. |
| Secondary | Relapse (recurrence) within follow-up | Up to 8 weeks | Proportion of participants with reappearance of dermatophytosis lesions at the same or contiguous site after achievement of clinical cure, within the follow-up period, with potassium hydroxide positivity where feasible. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07420894
GET https://conductscience.org/api/trials/v1/NCT07420894/registered