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Trial · NCT07421869

SNUH Immune Checkpoint Inhibitor-induced Hypothyroidism Recovery Trial

NCT07421869, Not applicable, Recruiting, Seoul National University Bundang Hospital

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. SNUH Immune Checkpoint Inhibitor-induced Hypothyroidism Recovery Trial. Trials, record NCT07421869. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07421869

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
SNUH Immune Checkpoint Inhibitor-induced Hypothyroidism Recovery Trial
NCT number
NCT07421869
Status
Recruiting
Phases
Not applicable
Enrollment
107 participants, estimated
Lead sponsor
Seoul National University Bundang Hospital
Conditions
Hypothyroidism
Interventions
Levothyroxine tapering
First posted
2026-02-19
Last updated
2026-02-19

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryProportion of participants who maintain discontinuation of levothyroxine for at least 6 monthsUp to 6 months after levothyroxine discontinuation
The number and proportion of participants who are able to remain off levothyroxine for at least 6 consecutive months without requiring re-initiation of treatment due to abnormal thyroid function (serum TSH level ≥10 μIU/mL).
SecondaryProportion of participants who can discontinue levothyroxineup to 3 years after study enrollment
The number and proportion of participants who were able to discontinue levothyroxine after dose reduction during the study follow-up period, regardless of whether the discontinuation was sustained. This includes any participant who temporarily stopped levothyroxine for any duration, even if the medication was later resumed.
SecondaryProportion of participants who maintain discontinuation of levothyroxine for at least 12 monthsUp to 12 months after levothyroxine discontinuation
The number and proportion of participants who are able to remain off levothyroxine for at least 12 consecutive months without requiring re-initiation of treatment due to abnormal thyroid function (serum TSH level ≥10 μIU/mL).
SecondaryProportion of participants who maintain discontinuation of levothyroxine for at least 36 monthsUp to 36 months after levothyroxine discontinuation
The number and proportion of participants who are able to remain off levothyroxine for at least 36 consecutive months without requiring re-initiation of treatment due to abnormal thyroid function (serum TSH level ≥10 μIU/mL).

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07421869

GET https://conductscience.org/api/trials/v1/NCT07421869/registered