Trial · NCT07437768
Vonoprazan Test for PPI Refractory GERD
NCT07437768, Not applicable, Enrolling by invitation, Fu Jen Catholic University Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Vonoprazan Test for PPI Refractory GERD. Trials, record NCT07437768. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07437768
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Vonoprazan Test for PPI Refractory GERD
- NCT number
- NCT07437768
- Status
- Enrolling by invitation
- Phases
- Not applicable
- Enrollment
- 100 participants, estimated
- Lead sponsor
- Fu Jen Catholic University Hospital
- Conditions
- Refractory GERD, NERD, PCAB
- Interventions
- Patients received a 4-week treatment of vonoprazan 20 mg once daily (VOCINTI®)
- First posted
- 2026-02-27
- Last updated
- 2026-02-27
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | All participants were evaluated using the following validated symptom questionnaires: The GERD Questionnaire | 4 weeks | The GERD Questionnaire (GerdQ) includes 4 positive predictors (heartburn, regurgitation, reflux-related sleep disturbance, and use of over-the-counter medications) and 2 negative predictors (epigastric pain and nausea) for GERD. The GerdQ score ranges from 0 to 18. A higher score indicates a higher probability of GERD and a greater symptom burden. A cutoff score of 8 or higher is generally used to identify patients with a high likelihood of having GERD. |
| Secondary | The Reflux Symptom Index (RSI) | 4 weeks | The Reflux Symptom Index (RSI) consists of 9 items (e.g., hoarseness, frequent throat clearing, and globus sensation), each rated on a scale from 0 (no problem) to 5 (severe) based on the severity of symptoms. Minimum score: 0 Maximum score: 45 |
| Secondary | The 5-item Brief Symptom Rating Scale (BSRS-5) | 4 weeks | The BSRS-5 score ranges from 0 to 20. A higher score indicates greater psychological distress. The 5-item Brief Symptom Rating Scale (BSRS-5) was used to screen for common psychiatric conditions, such as anxiety and depression; a score ≥ 6 indicates potential psychological morbidity. |
| Secondary | The Pittsburgh Sleep Quality Index (PSQI) | 4 weeks | The Pittsburgh Sleep Quality Index (PSQI) is a 7-item self-rated questionnaire used to assess sleep quality over the preceding month; a global PSQI score \> 5 indicates poor sleep quality or sleep disturbance. The PSQI global score ranges from 0 to 21. A higher score indicates poorer sleep quality. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07437768
GET https://conductscience.org/api/trials/v1/NCT07437768/registered