Trial · NCT07447739
Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively?
NCT07447739, Phase 2, Not yet recruiting, Khang Nguyen
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively? Trials, record NCT07447739. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07447739
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively?
- NCT number
- NCT07447739
- Status
- Not yet recruiting
- Phases
- Phase 2
- Enrollment
- 100 participants, estimated
- Lead sponsor
- Khang Nguyen
- Conditions
- Respiratory Distress Syndrome (RDS), Bronchopulmonary Dysplasia (BPD)
- Interventions
- Betamethasone
- First posted
- 2026-03-03
- Last updated
- 2026-03-03
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The rate of successful respiratory weaning | From initiation of treatment until 7 days after treatment completion | * Defined by a 20% reduction from baseline in mean airway pressure or FiO2 if patient remains intubated * or successful extubation and maintenance of extubation for 7 days after betamethasone completion |
| Secondary | The incidence of adverse events | During betamethasone administration period (5 days) | The incidence of hyperglycemia (\>150 mg/dL) during administration period |
| Secondary | The incidence of adverse events | From the time of initiation of betamethasone until the time of NICU discharge or 52 weeks of age, whichever comes first | The incidence of hypertension (requiring medication) anytime during hospitalization |
| Secondary | The incidence of adverse events | During betamethasone administration period and up to 72 hours after completion of betamethasone administration | The incidence of gastrointestinal perforation (during or less than 72 hours after treatment completion) |
| Secondary | The incidence of adverse events | From the time of initiation of betamethasone until the time of NICU discharge or 52 weeks of age, whichever comes first | The incidence of culture-positive infection that requires treatment |
| Secondary | The incidence of mortbidities associated with extreme prematurity | From admission until the time of NICU discharge or 52 weeks of age, whichever comes first | The incidence of * Severe intraventricular hemorrhage * Periventricular leukomalacia * Retinopathy of prematurity * Hemodynamically signifcant patent ductus arteriosus |
| Secondary | Anthropometric measurements | From discharge to 24 months corrected age | weight at the time of discharge (in grams and percentile rank using Fenton growth curve 2013 for gestational age) and at 24 months corrected age (in grams and their corresponding percentile rank for age using CDC growth chart 0-36 months) |
| Secondary | Anthropometric measurements | From discharge to 24 months corrected age | length at the time of discharge (in centimeters and percentile rank using Fenton growth curve 2013 for gestational age) and at 24 months corrected age (in centimeters and their corresponding percentile rank for age using CDC growth chart 0-36 months) |
| Secondary | Anthropometric measurements | From discharge to 24 months corrected age | Head circumference at the time of discharge (in centimeters and percentile rank using Fenton growth curve 2013 for gestational age) and at 24 months corrected age (in centimeters and their corresponding percentile rank for age using CDC growth chart 0-36 months) |
| Secondary | Neurodevelopmental outcomes | at 24 months corrected age | the results of evaluation utilizing the Bayley Scales of Infant Development. The minimum score is 40 and the maximun score is 160, with a higher score represents better outcome. The score of 100 is average, and 15 points represents 1 standard deviation either way. |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 19052552 | BACKGROUND |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07447739
GET https://conductscience.org/api/trials/v1/NCT07447739/registered