Trial · NCT07450963
Cadonilimab Combined With RT in LACC Patients Ineligible for CCRT
NCT07450963, Phase 2, Not yet recruiting, Ruijin Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cadonilimab Combined With RT in LACC Patients Ineligible for CCRT. Trials, record NCT07450963. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07450963
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cadonilimab Combined With RT in LACC Patients Ineligible for CCRT
- NCT number
- NCT07450963
- Status
- Not yet recruiting
- Phases
- Phase 2
- Enrollment
- 45 participants, estimated
- Lead sponsor
- Ruijin Hospital
- Conditions
- Locally Advanced Cervical Cancer
- Interventions
- Cadonilimab, RT
- First posted
- 2026-03-05
- Last updated
- 2026-03-05
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Complete response (CR) rate | 5 year | The proportion of patients with disappearance of all target lesions (cervix and lymph nodes), no new lesions, and normalisation of tumour markers (e.g., SCC Ag), confirmed by pelvic MRI and/or PET CT and maintained for at least 4 weeks according to RECIST v1.1 |
| Secondary | 2 year progression free survival | 2 year | |
| Secondary | 2 year local control rate | 2 year | |
| Secondary | 2 year locoregional control rate | 2 year | |
| Secondary | 5 year overall survival | 5 year | |
| Secondary | Acute adverse events (AEs) | up to 3 months | adverse events (AEs) according to CTCAE v5.0 |
| Secondary | Late AE | up to 5 years | RTOG/EORTC |
| Secondary | Quality of life assessed by EORTC QLQ C30 score | up to 5 years | change from baseline in EORTC QLQ C30 score (0-100), higher scores mean a better outcome. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07450963
GET https://conductscience.org/api/trials/v1/NCT07450963/registered