ConductScience.org, home

Trial · NCT07452913

Metformin, Empagliflozin With Sitagliptin vs Linagliptin in Type 2 Diabetes

NCT07452913, Phase 4, Enrolling by invitation, Bahria University

3 sourcestrials-2026-11-12-0.5.0

Download JSON
Cite this record

ConductScience Library. Metformin, Empagliflozin With Sitagliptin vs Linagliptin in Type 2 Diabetes. Trials, record NCT07452913. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07452913

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Metformin, Empagliflozin With Sitagliptin vs Linagliptin in Type 2 Diabetes
NCT number
NCT07452913
Status
Enrolling by invitation
Phases
Phase 4
Enrollment
110 participants, estimated
Lead sponsor
Bahria University
Conditions
Type 2 Diabetes Mellitus
Interventions
Metformin+ Empagliflozin + Sitagliptin, Metformin + Empagliflozin + Linagliptin
First posted
2026-03-05
Last updated
2026-03-05

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPrimary Outcome3 MonthsChange in HbA1c levels in %
SecondarySecondary Outcome : changes in weight from baseline to 12 weeks (kg)12 weeksthe study will measure percentage change in weight from baseline to 12 weeks and proportion of participants achieving weight loss 1- 3 kg as national institute of health. Time Frame: 12 weeks
SecondarySecondary Outcome: changes in BMI from baseline to 12 weeks (kg/m²).12 weeksThe study will measure percentage changes in BMI from baseline to 12 weeks and proportion of participants achieving required BMI
SecondarySecondary outcome: changes in lipid profile (TC, TG, HDL, LDL, VLDL) from baseline to 12 weeks (mg/dl)12 weeksThe study will measure the changes in lipid profiles level from baseline to 12 weeks to evaluate the efficacy of triple vs initial triple therapy
SecondarySecondary Outcome: To measure safety of Adverse Effects (nausea, vomiting, diarrhea, constipation, UTIs, flu like symptoms, headache, hypoglycemia, weight gain) from baseline to 12 weeks12 weeks
The study will measure the safety of Adverse Effects (nausea, vomiting, diarrhea, constipation, UTIs, flu like symptoms, headache, hypoglycemia, weight gain) from baseline to 12 weeks to evaluate the safety of triple vs initial triple therapy

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers10

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
11953758BACKGROUNDPubMed
35307801BACKGROUNDPubMed
37294638BACKGROUNDPubMed
37414069BACKGROUNDPubMed
38423026BACKGROUNDPubMed
39030553BACKGROUNDPubMed
39096426BACKGROUNDPubMed
39353925BACKGROUNDPubMed
39596449BACKGROUNDPubMed
39723311BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07452913

GET https://conductscience.org/api/trials/v1/NCT07452913/registered