Trial · NCT07456670
Caffeine for Infants Born at 28 to 34 Weeks Receiving Respiratory Support
NCT07456670, Phase 2, Not yet recruiting, Queen's University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Caffeine for Infants Born at 28 to 34 Weeks Receiving Respiratory Support. Trials, record NCT07456670. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07456670
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Caffeine for Infants Born at 28 to 34 Weeks Receiving Respiratory Support
- NCT number
- NCT07456670
- Status
- Not yet recruiting
- Phases
- Phase 2
- Enrollment
- 62 participants, estimated
- Lead sponsor
- Queen's University
- Conditions
- Preterm Birth, Caffeine, Neonatal Outcomes
- Interventions
- Caffeine, Placebo
- First posted
- 2026-03-06
- Last updated
- 2026-03-10
Source ClinicalTrials.gov
Registered outcomes29
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Recruitment/Eligibility Proportion | Through study completion, up to 24 months | Ratio of enrolled/randomized infants to total eligible infants screened. |
| Primary | Treatment Adherence Proportion | From randomization until 24 hours after weaning from respiratory support | Percentage of per-protocol doses (caffeine/placebo) successfully administered |
| Primary | Retention Proportion | Through study completion, up to 24 months | Percentage of randomized infants who complete the study protocol until NICU discharge |
| Secondary | Time to Discharge Alive from the NICU | From the date of randomization until the date of discharge alive from NICU, assessed up to 24 months | Hours from the time of randomization to the time of discharge alive from the NICU |
| Secondary | Parent/Guardian Acceptability | Within 7 days prior to infant's NICU discharge | Frequency distribution of Likert-scale responses on the parent satisfaction survey |
| Secondary | Healthcare Provider Acceptability | Through recruitment completion, an average of 24 months | Thematic analysis of healthcare provider focus group transcripts regarding protocol viability |
| Secondary | Data Completeness | At the end of the recruitment period, approximately 24 months | Proportion of missing data points across all secondary clinical outcomes. |
| Secondary | Significant Apnea Frequency | From randomization until 24 hours after weaning from respiratory support | Mean number of apneas per day requiring intervention (stimulation, or ventilation) |
| Secondary | Total Duration of Respiratory Support | From the date of randomization until the date of discharge alive from NICU or date of death from any cause, whichever came first, assessed up to 24 months | Total hours spent on invasive and non-invasive mechanical ventilation |
| Secondary | Duration of Invasive Support | From the date of randomization until the date of discharge alive from NICU or date of death from any cause, whichever came first, assessed up to 24 months | Total hours spent specifically on invasive mechanical ventilation (intubation) |
1 to 10 of 29Source ClinicalTrials.gov
See all 29 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers6
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07456670
GET https://conductscience.org/api/trials/v1/NCT07456670/registered?page=2