Trial · NCT07479732
Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma
NCT07479732, Phase 1, Phase 2, Recruiting, Peking University People's Hospital
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma. Trials, record NCT07479732. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07479732
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma
- NCT number
- NCT07479732
- Status
- Recruiting
- Phases
- Phase 1, Phase 2
- Enrollment
- 56 participants, estimated
- Lead sponsor
- Peking University People's Hospital
- Conditions
- Osteosarcoma, Osteosarcoma Metastatic
- Interventions
- Liposomal Irinotecan, Apatinib in arm1
- First posted
- 2026-03-18
- Last updated
- 2026-03-18
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Recommended Phase II Dose (RP2D) | 6 weeks | Determination of the recommended phase II dose based on dose-limiting toxicity (DLT) observed during the first two cycles (6 weeks). |
| Secondary | Objective Response Rate (ORR) | Every 6 weeks up to 24 months | |
| Secondary | Progression-Free Survival (PFS) | From treatment initiation until disease progression or death, up to 24 months | |
| Secondary | Overall Survival，OS | From treatment initiation until death from any cause, up to 24 months |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers5
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07479732
GET https://conductscience.org/api/trials/v1/NCT07479732/registered