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Trial · NCT07483801

DECODE - Haemodynamic Effects Of Semaglutide and Tirzepatide - a Series of Pilot Studies

NCT07483801, Phase 4, Not yet recruiting, Cambridge University Hospitals NHS Foundation Trust

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. DECODE - Haemodynamic Effects Of Semaglutide and Tirzepatide - a Series of Pilot Studies. Trials, record NCT07483801. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07483801

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
DECODE - Haemodynamic Effects Of Semaglutide and Tirzepatide - a Series of Pilot Studies
NCT number
NCT07483801
Status
Not yet recruiting
Phases
Phase 4
Enrollment
112 participants, estimated
Lead sponsor
Cambridge University Hospitals NHS Foundation Trust
Conditions
Cardiovascular Diseases
Interventions
semaglutide, Tirzepatide
First posted
2026-03-19
Last updated
2026-03-19

Source ClinicalTrials.gov

Registered outcomes21

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimarySub-study 1A:Change in forearm blood flow parameters after infusion of semaglutide (Ratio)2-2.5 months from screening to follow-upRatio, expressed as a number (no units as this is a ratio)
PrimarySub-study 1A:Change in forearm blood flow parameters after infusion of semaglutide (Absolute flow)2-2.5 months from screening to follow-upAbsolute flow in the infused arm, in mL/min/100 mL
PrimarySub-study 1A: Change in forearm blood flow parameters after infusion of semaglutide (Percentage Change)2-2.5 months from screening to follow-upPercentage change in the infused arm, in %
PrimarySub-study 1B: Change in forearm blood flow parameters after infusion of tirzepatide (Absolute flow)2-2.5 months from screening to follow-upAbsolute flow in the infused arm, in mL/min/100 mL
PrimarySub-study 1B: Change in forearm blood flow parameters after infusion of tirzepatide (Ratio)2-2.5 months from screening to follow-upRatio, expressed as a number (no units as this is a ratio)
PrimarySub-study 1B: Change in forearm blood flow parameters after infusion of tirzepatide (Percent Change)2-2.5 months from screening to follow-upPercentage change in the infused arm, in %
PrimarySub-study 1C: Change in forearm blood flow parameters after infusion of semaglutide or tirzepatide or saline (Absolute flow)2-2.5 months from screening to follow-upAbsolute flow in the infused arm, in mL/min/100 mL
PrimarySub-study 1C: Change in forearm blood flow parameters after infusion of semaglutide or tirzepatide or saline (Ratio)2-2.5 months from screening to follow-upRatio, expressed as a number (no units as this is a ratio)
PrimarySub-study 1C: Change in forearm blood flow parameters after infusion of semaglutide or tirzepatide or saline (Percentage change)2-2.5 months from screening to follow-upPercentage change in the infused arm, in %
PrimarySub-study 2A: Changes in cardiovascular haemodynamic variables after administration of semaglutide (Blood pressure)2-2.5 months from screening to follow-upBlood pressure measured in mmHg

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07483801

GET https://conductscience.org/api/trials/v1/NCT07483801/registered?page=2