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Trial · NCT07493161

Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL

NCT07493161, Not applicable, Recruiting, Institute of Hematology & Blood Diseases Hospital, China

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL. Trials, record NCT07493161. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07493161

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL
NCT number
NCT07493161
Status
Recruiting
Phases
Not applicable
Enrollment
110 participants, estimated
Lead sponsor
Institute of Hematology & Blood Diseases Hospital, China
Conditions
Ph+ ALL
Interventions
Olverembatinib, Venetoclax, Blinatumomab, Chemotherapy Backbone Regimens, Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT), Inotuzumab ozogamicin
First posted
2026-03-25
Last updated
2026-07-23

Source ClinicalTrials.gov

Registered outcomes12

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryRate of BCR::ABL1 ≤0.01% at 90 days (after three cycles of treatment)up to 90 days
PrimaryModified Event-Free Survival (mEFS) from start of InO consolidationFrom the start of InO consolidation therapy up to 2 years
SecondaryOverall Survivalup to 5 years
SecondaryRelapse-Free Survivalup to 5 years
SecondaryCumulative incidence of molecular relapseup to 5 years
SecondaryCumulative incidence of hematologic relapseup to 5 years
SecondaryProportion of patients with next-generation sequencing minimal residual disease <0.01% after three cycles of treatment (90 days)up to 90 days
SecondaryProportion of patients with next-generation sequencing minimal residual disease <0.01% at the end of consolidation therapyup to 1 year
SecondaryIncidence of treatment-related cardiovascular eventsup to 5 years from the initiation of treatment
SecondaryProportion of patients with BCR::ABL1 ≤0.01% at completion of consolidation therapyup to 9 months

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07493161

GET https://conductscience.org/api/trials/v1/NCT07493161/registered