Trial · NCT07495748
Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma
NCT07495748, Not applicable, Not yet recruiting, Foundation University Islamabad
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma. Trials, record NCT07495748. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07495748
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma
- NCT number
- NCT07495748
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 70 participants, estimated
- Lead sponsor
- Foundation University Islamabad
- Conditions
- Melasma
- Interventions
- topical 3% tranexamic acid solution, Topical 30% metformin cream
- First posted
- 2026-03-27
- Last updated
- 2026-03-27
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Mean reduction in MASI (MASI) score | 12 weeks | Compare the mean reduction in MASI scores from baseline to 12 weeks between topical 30% metformin and 3% tranexamic acid. |
| Secondary | Patients with adverse effects | 12 weeks | Proportion of participants developing adverse effects (erythema, burning, peeling/dryness, or dyspigmentation) during treatment, compared between groups at follow-up visits. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07495748
GET https://conductscience.org/api/trials/v1/NCT07495748/registered